This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Metoprolol is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins).
Metoprolol is used to treat angina (chest pain) and hypertension ( high blood pressure ).
Metoprolol is also used to lower your risk of death or needing to be hospitalized for heart failure .
Metoprolol injection is used during the early phase of a heart attack to lower the risk of death.
Indications
Metoprolol is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins).
Metoprolol is used to treat angina (chest pain) and hypertension ( high blood pressure ).
Metoprolol is also used to lower your risk of death or needing to be hospitalized for heart failure .
Metoprolol injection is used during the early phase of a heart attack to lower the risk of death.
Contraindications
You should not use this medicine if you are allergic to metoprolol, or other beta-blockers ( atenolol , carvedilol , labetalol , nadolol , nebivolol , propranolol , sotalol , and others), or if you have:
a serious heart problem such as heart block, sick sinus syndrome, or slow heart rate; severe circulation problems; severe heart failure (that required you to be in the hospital); or a history of slow heart beats that have caused you to faint.
To make sure this medicine is safe for you, tell your doctor if you have:
asthma , chronic obstructive pulmonary disease ( COPD ), sleep apnea , or other breathing disorder; diabetes (taking metoprolol may make it harder for you to tell when you have low blood sugar ); liver disease; congestive heart failure; problems with circulation (such as Raynaud's syndrome ); a thyroid disorder; or pheochromocytoma (tumor of the adrenal gland).
Do not give this medicine to a child without medical advice.
Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether metoprolol will harm an unborn baby. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating hypertension may outweigh any risks to the baby.
Ask a doctor before using this medicine if you are breast-feeding. Metoprolol can pass into breast milk and may cause dry skin , dry mouth, diarrhea , constipation , or slow heartbeats in your baby.
Side Effects
Get emergency medical help if you have signs of an allergic reaction to metoprolol: hives ; difficulty breathing; swelling of your face, lips, tongue, or throat.
Metoprolol may cause serious side effects. Call your doctor at once if you have:
very slow heartbeats; a light-headed feeling, like you might pass out; shortness of breath (even with mild exertion), swelling, rapid weight gain; or cold feeling in your hands and feet.
Common side effects of metoprolol may include:
dizziness ; tired feeling; depression ; confusion; memory problems; nightmares; trouble sleeping; diarrhea; mild itching or rash.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
You should not use metoprolol if you have a serious heart problem ( heart block , sick sinus syndrome, slow heart rate ), severe circulation problems, severe heart failure, or a history of slow heart beats that caused fainting.
High Risk Groups
You should not use metoprolol if you have a serious heart problem ( heart block , sick sinus syndrome, slow heart rate ), severe circulation problems, severe heart failure, or a history of slow heart beats that caused fainting.
Adult Dosage
100 to 200 mg (150 (150)) 24 hourly PO — For Hypertension Initially given 100 mg.Maintainance dose is 200 mg Can be increased up to 400 mg
5 mg (5 (5)) As recommended. IV — For Cardiac Arrythmia rate is 2mg/min may be repeated at intervals of 5 min to a total dose of 10-15 mg .Maintainence therapy dose should not exceed than 50 mg (PO) given 3 times a day ,4 to 6 hrz after IV therapy
50 to 100 mg (75 (75)) 12 hourly PO — For Angina Pectoris
50 to 300 mg (180 (175)) 8 hourly PO — For Cardiac Arrythmia
Scraped Dose — Take metoprolol exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.
Metoprolol should be taken with a meal or just after a meal.
Take the medicine at the same time each day.
Swallow the capsule whole and do not crush, chew, break, or open it.
A Toprol XL tablet can be divided in half if your doctor has told you to do so. Swallow the half-tablet whole, without chewing or crushing.
Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
You will need frequent medical tests, and your blood pressure will need to be checked often.
If you need surgery, tell the surgeon ahead of time that you are using this medicine.
You should not stop using this medicine suddenly. Stopping suddenly may make your condition worse.
If you have high blood pressure, keep using metoprolol even if you feel well. High blood pressure often has no symptoms. You may need to use this medicine for the rest of your life.
Store at room temperature away from moisture and heat.
Metoprolol injection is given as an infusion into a vein. A healthcare provider will give you this injection in a medical setting where your heart and blood pressure can be monitored. The injections are given for only a short time before switching you to the oral form of this medicine.
Child Dosage
2.5 to 4 mg/kg (3.2 (3.25)) 12 hourly Oral — -
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Tell your doctor about all your current medicines. Many drugs can interact with metoprolol, especially:
any other heart or blood pressure medications; epinephrine (Epi-Pen); an antidepressant; an ergot medicine-- dihydroergotamine , ergonovine, ergotamine , methylergonovine ; or an MAO inhibitor-- isocarboxazid , linezolid , phenelzine , rasagiline , selegiline , tranylcypromine .
This list is not complete and many other drugs may interact with metoprolol. This includes prescription and over-the-counter medicines, vitamins , and herbal products . Not all possible drug interactions are listed here.
Storage
Inj Store at room temperature, Below 30°C. Do not Freeze. Protect from Sunlight. Tab Store Between 15°C-25°C. Protect from Sunlight and Moisture.