Mexiletine
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Mexiletine affects the way that your heart beats.
Mexiletine is used to treat seriously irregular heartbeats.
Mexiletine may also be used for purposes not listed in this medication guide.
Indications
Mexiletine affects the way that your heart beats.
Mexiletine is used to treat seriously irregular heartbeats.
Mexiletine may also be used for purposes not listed in this medication guide.
Contraindications
You should not use mexiletine if you are allergic to it, or if you have:
a serious heart condition such as "AV block" (unless you have a pacemaker).
To make sure mexiletine is safe for you, tell your doctor if you have:
liver disease ; congestive heart failure; epilepsy or other seizure disorder; a weak immune system (caused by disease or by using certain medicine); or if you have recently taken other heart rhythm medicines ( disopyramide , lidocaine , quinidine , or others).
FDA pregnancy category C. It is not known whether mexiletine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using mexiletine.
Mexiletine can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.
Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Mexiletine may cause you to have abnormal liver function tests, especially if you also have congestive heart failure , or blood circulation problems.
Mexiletine may cause serious side effects. Call your doctor at once if you have:
chest pain; a new or a worsening irregular heartbeat pattern; or liver problems --nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Common side effects of mexiletine may include:
heartburn , upset stomach , nausea, vomiting ; dizziness, feeling lightheaded; tremors, feeling nervous; problems with coordination; or blurred vision.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
You should not use mexiletine if you have a serious heart condition such as "AV block" (unless you have a pacemaker).
Mexiletine may cause you to have abnormal liver function tests, especially if you also have congestive heart failure, or blood circulation problems.
High Risk Groups
You should not use mexiletine if you have a serious heart condition such as "AV block" (unless you have a pacemaker).
Mexiletine may cause you to have abnormal liver function tests, especially if you also have congestive heart failure, or blood circulation problems.
Adult Dosage
2.857 to 5.714 mg/kg (4.3 (4.2855)) 8 hourly PO — -
Scraped Dose — Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Mexiletine is usually given at first in a hospital.
Take mexiletine with food or an antacid to lessen stomach upset .
Your heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG).
Do not skip doses, change your dosing schedule, or stop taking mexiletine without talking to your doctor. Changing your schedule could make your condition much worse.
Store at room temperature away from moisture, heat, and light.
Child Dosage
2.5 to 4 mg/kg (3.2 (3.25)) 8 hourly Oral —
Neonatal Dosage
2.5 to 4 mg/kg (3.2 (3.25)) 8 hourly Oral —
Drug Interactions
Other drugs may interact with mexiletine, including prescription and over-the-counter medicines, vitamins , and herbal products . Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Storage
Caps Store Below 40°C. Protect from Sunlight and Moisture.
Available Brands in Pakistan
No brands are recorded for this generic.
