Mianserin
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Mianserin was introduced in 1976 as an antidepressant, Mianserin has a novel tetracyclic structure and a pharmacological action that differed from previous antidepressant drugs. It is used to treat depression, nerve pain, insomnia, bed-wetting in children older than six years.
Indications
Mianserin is primarily indicated in conditions like Anxiety, Depression.
Contraindications
Mianserin is contraindicated in conditions like Mania.
Side Effects
The severe or irreversible adverse effects of Mianserin, which give rise to further complications include Hepatic damage, Jaundice, Jaundice, Breast cancer, Polyarthropathy. Mianserin produces potentially life-threatening effects which include Agranulocytosis, Blood dyscrasias, Aplastic Anemia, Anxiety. which are responsible for the discontinuation of Mianserin therapy. The signs and symptoms that are produced after the acute overdosage of Mianserin include Death. The symptomatic adverse reactions produced by Mianserin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Giddiness, Increased appetite.
Warnings
Caution should be done in the patient with bone marrow depression, usually presenting as Granulocytopenia or agranulocytosis, has been reporting during treatment. If a patient shows fever, sore throat, stomatitis or other signs of infection, treatment should be stopped and a full blood count should be discontinued. Treatment should be discontinued if convulsions or jaundice occurs.
High Risk Groups
Drug should not be given to Pregnant Mothers, Geriatrics, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
60 to 90 mg (75 (75)) 24 hourly PO — Initial dose 30 mg
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
Mianserin is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholApraclonidine (HCl)Avoid concomitant use.Clonidine (HCl)FosphenytoinPhenytoin (Na)Propranolol (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tab Store at room temperature. Protect from Sunlight.
Available Brands in Pakistan
No active brands are currently recorded for this generic.
2 records are present but flagged "Unverified / Legacy" and excluded.