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Medicines/Generics/Mitomycin C

Mitomycin C

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview
Mitomycin is used in combination with other cancer drugs to treat cancer of the stomach and pancreas. Mitomycin may also be used for purposes not listed in this medication guide.
Indications
Mitomycin is used in combination with other cancer drugs to treat cancer of the stomach and pancreas. Mitomycin may also be used for purposes not listed in this medication guide.
Contraindications
You should not be treated with mitomycin if you are allergic to it, or if you have: low levels of platelets in your blood; bone marrow suppression; or active bleeding or any risk of bleeding. Tell your doctor if you have ever had: kidney disease; heart disease ; or asthma , chronic obstructive pulmonary disease (COPD), sleep apnea , or other breathing disorder. Mitomycin may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant. You should not breastfeed while using mitomycin.
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat. Mitomycin can damage red blood cells, which may cause irreversible kidney failure . Tell your doctor right away if you have unusual bruising or bleeding, pale skin, confusion, tiredness or irritability, stomach pain, bloody diarrhea , red or pink urine, swelling, rapid weight gain, and little or no urinating. Mitomycin may cause serious side effects. Call your doctor at once if you have: signs of infection (fever, weakness, cold or flu symptoms, skin sores, frequent or recurring illness); wheezing , chest tightness, new or worsening cough , trouble breathing; blisters or ulcers in your mouth, red or swollen gums, trouble swallowing; or pain, burning, redness, swelling, irritation, or skin changes where the injection was given. Common side effects of mitomycin may include: fever or other signs of infection; nausea , vomiting , diarrhea, loss of appetite; mouth sores; drowsiness , headache ; blurred vision; or temporary hair loss . This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Mitomycin can damage red blood cells, which may cause irreversible kidney failure. Tell your doctor right away if you have unusual bruising or bleeding, pale skin, confusion, tiredness or irritability, stomach pain, bloody diarrhea, red or pink urine, swelling, rapid weight gain, and little or no urinating. Mitomycin can also weaken (suppress) your immune system, and you may get an infection more easily. Call your doctor if you have signs of infection (fever, weakness, cold or flu symptoms, skin sores, frequent or recurring illness).
High Risk Groups
Mitomycin can damage red blood cells, which may cause irreversible kidney failure. Tell your doctor right away if you have unusual bruising or bleeding, pale skin, confusion, tiredness or irritability, stomach pain, bloody diarrhea, red or pink urine, swelling, rapid weight gain, and little or no urinating. Mitomycin can also weaken (suppress) your immune system, and you may get an infection more easily. Call your doctor if you have signs of infection (fever, weakness, cold or flu symptoms, skin sores, frequent or recurring illness).
Adult Dosage
10 to 20 mg/sq.metre (15 (15)) As recommended. IV Inf — Every 4 to 6 weeks
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Other drugs may affect mitomycin, including prescription and over-the-counter medicines, vitamins , and herbal products . Tell your doctor about all your current medicines and any medicine you start or stop using.
Storage
Inj (reconstituted soln) Store at room temperature or refrigerator. Protect from Sunlight. Use within 2 weeks if refrigerated and within 1 week if kept at room temperature.

Available Brands in Pakistan

2 active brands listed alphabetically.

MITOMYCIN

Active

AL-HABIB PHARMACEUTICALS.

DML: MITOMYCIN

Inj

MITOMYCIN-C

Active

S. EJAZUDDIN & COMPANY

DML: MITOMYCIN-C

Inj

1 additional record is present but flagged "Unverified / Legacy" and not listed.