Moclobemide

Moclobemide is a type of monoamine oxidase (MAO) inhibitor used to treat certain types of mental depression. It works by reversibly blocking the action of a chemical substance known as monoamine oxidase A (MAO-A) in the nervous system. Although this medicine is very effective for certain patients, it may also cause some unwanted reactions if taken the wrong way. It is very important to avoid certain beverages and medicines while you are using moclobemide. Your doctor may provide a list as a reminder of which products you should avoid. This medicine is available only with your doctor's prescription.

Moclobemide is a type of monoamine oxidase (MAO) inhibitor used to treat certain types of mental depression. It works by reversibly blocking the action of a chemical substance known as monoamine oxidase A (MAO-A) in the nervous system. Although this medicine is very effective for certain patients, it may also cause some unwanted reactions if taken the wrong way. It is very important to avoid certain beverages and medicines while you are using moclobemide. Your doctor may provide a list as a reminder of which products you should avoid. This medicine is available only with your doctor's prescription.

Moclobemide is contraindicated in conditions like Pheochromocytoma, Thyrotoxicosis, Acute confusion states.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Stop taking this medicine and get emergency help immediately if any of the following effects occur: Fast or racing heartbeat pounding or irregular heartbeat neck stiffness severe throbbing headache which starts at the back of the head and radiates forward slow heartbeat Check with your doctor immediately if any of the following side effects occur: More common Mild to moderate headache, or pressure in the head Less common Anxiety blurred vision or other changes in vision dizziness, faintness, or lightheadedness, especially when getting up from a sitting or lying position suddenly fast or racing heartbeat high blood pressure irritability nervousness pounding or irregular heartbeat restlessness unusual tiredness or weakness Rare Aggressive behavior bleeding gums burning, prickling, or tingling sensations chest pain confusion increased depression, or other mood and mental changes difficulty with speaking fast, slow, or irregular heart beat feeling of something in the eye general feeling of illness headache (severe) increase in urination increased sensitivity of eyes to light irregular or prolonged menstrual periods irritation or soreness of the mouth itching, redness, and swelling of the eye loss of balance control loss of interest in self or surroundings memory problems pain or straining to pass urine or stool painful urination restlessness or desire to keep moving ringing or noise in the ears seeing, hearing, or feeling things that are not there skin rash, hives, or itching stomach pain or burning slow heartbeat troubled breathing twisting movements of body uncontrolled movements, especially of the face, neck, and back Get emergency help immediately if any of the following symptoms of overdose occur: Symptoms of overdose Agitation confusion convulsions (seizures) decreased reflexes extreme drowsiness high blood pressure loss of memory nausea slurred speech vomiting Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Dryness of mouth trembling or shaking of arms or legs Less common or rare Abdominal or stomach pain or discomfort change in your sense of taste constipation diarrhea dizziness drowsiness feeling of warmth of the face, neck, arms, and occasionally upper chest heartburn or indigestion increased or decreased appetite increased sweating joint or muscle pain nightmares trouble sleeping. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Pharmacologic Class: Monoamine Oxidase Inhibitor, Type A

Patient should be closely monitored during early antidepressant therapy until improvement in depression is observed because suicide is an inherent risk in depressed patients. Moclobemide should be avoided in exited or agitated patients or those with severe hepatic (liver) impairment. Care should also required in patients with thyrotoxicosis as moclobemide may precipitate hypertensive reaction.

Drug should not be given to Pediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Geriatrics. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

150 mg (150 (150)) 24 hourly PO — Maintenance. 300 mg (300 (300)) 24 hourly PO — Dose may be increased by 600 mg.

( ) — Not recommended in this age group

( ) — Not recommended in this age group

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Amitriptyline Amoxapine Amphetamine Apraclonidine Benzphetamine Brimonidine Bupropion Carbamazepine Carbidopa Carbinoxamine Clomipramine Codeine Cyclobenzaprine Cyproheptadine Desipramine Deutetrabenazine Dexfenfluramine Dextroamphetamine Dextromethorphan Diethylpropion Dothiepin Doxepin Doxylamine Eliglustat Fenfluramine Guanadrel Guanethidine Hydroxytryptophan Imipramine Isometheptene Levodopa Levomethadyl Lisdexamfetamine Lofepramine Maprotiline Mavacamten Mazindol Meperidine Methamphetamine Methotrimeprazine Methyldopa Mirtazapine Nefopam Nortriptyline Opipramol Ozanimod Phendimetrazine Phenmetrazine Phentermine Phenylalanine Protriptyline Pseudoephedrine Reserpine Safinamide Selegiline Sibutramine Solriamfetol Sumatriptan Tetrabenazine Tramadol Tranylcypromine Trazodone Trimipramine Tryptophan Venlafaxine Viloxazine Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Alfentanil Atropine Belzutifan Benzhydrocodone Buspirone Butorphanol Cilostazol Clovoxamine Clozapine Difenoxin Dihydrocodeine Diphenoxylate Dolasetron Droperidol Ethchlorvynol Femoxetine Fentanyl Frovatriptan Granisetron Guarana Hydrocodone Hydromorphone Iobenguane I 123 Iobenguane I 131 Kava Lasmiditan Levorphanol Licorice Lithium Ma Huang Mate Metaxalone Methadone Methylene Blue Metoclopramide Midodrine Morphine Morphine Sulfate Liposome Nalbuphine Naratriptan Nebivolol Nefazodone Norepinephrine Ondansetron Oxycodone Oxymetazoline Oxymorphone Palonosetron Pentazocine Phenobarbital Primidone Reboxetine Remifentanil St John's Wort Sufentanil Tamoxifen Tyrosine Ziprasidone Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Ginseng

Tab Store at room temperature. Protect from Moisture.