Molgramostim
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Molgramostim is a human growth factor made by recombinant DNA technology with actions and uses similar to Filgrastim. It stimulates the production of white blood cells in bone marrow. Molgramostim is used to increase the white blood cell production in patient whose bone marrow function is depressed by cancer therapy. Molgramostim is also being used in the treatment of AIDS.
Indications
Molgramostim is primarily indicated in conditions like Acceleration of myeloid recovery following bone marrow transplantation, Adjunct in ganciclovir treatment, AIDS, Aplastic anemia, Bone marrow transplantation, Cytotoxic chemotherapy, Leukopenia, Myelodysplastic syndrome, and can also be given in adjunctive therapy as an alternative drug of choice in Cancer.
Contraindications
Molgramostim is contraindicated in conditions like Myeloid leukemia.
Side Effects
Molgramostim produces potentially life-threatening effects which include Cardiac arrhythmias, Cardiac failure, Anaphylactic reactions. which are responsible for the discontinuation of Molgramostim therapy.vThe signs and symptoms that are produced after the acute overdosage of Molgramostim include Convulsions, Cerebrovascular disorders.The symptomatic adverse reactions produced by Molgramostim are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Fatigue, Nausea, Vomiting, Anorexia, Diarrhea, Dyspnea, Abdominal pain, Chills, Rashes, Confusion, Pruritus, Sweating, Hypotension, Flushing, Asthenia, Stomatitis, Syncope, Chest pain, Rigors.
Warnings
Caution in the patient with pre-existing pulmonary disease or a history of autoimmune disease. Regular monitoring of the white blood, differential blood counts, platelet count, hematocrit and serum albumin level is very important, safety in pregnancy is not established.
High Risk Groups
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
1 to 10 ug/kg (5.5 (5.5)) 24 hourly IV Inf — -
1 to 10 ug/kg (5.5 (5.5)) 24 hourly SC — -
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
No data regarding the interactions of Molgramostim was found.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No brands are recorded for this generic.