Medicines/Generics/Moxifloxacin

Moxifloxacin

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview

Moxifloxacin is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic that fights bacteria in the body. Moxifloxacin is used to treat different types of bacterial infections of the skin, sinuses, lungs, or stomach. Fluoroquinolone antibiotics can cause serious or disabling side effects that may not be reversible. Moxifloxacin should be used only for infections that cannot be treated with a safer antibiotic. Moxifloxacin may also be used for purposes not listed in this medication guide.

Indications

Contraindications

You should not use moxifloxacin if you are allergic to moxifloxacin or other fluoroquinolones ( ciprofloxacin , gemifloxacin , levofloxacin, ofloxacin, norfloxacin, and others). Moxifloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body) , especially in the Achilles' tendon of the heel. This can happen during treatment or up to several months after you stop taking moxifloxacin. Tendon problems may be more likely to occur if you are over 60, if you take steroid medication, or if you have had a kidney, heart, or lung transplant. Tell your doctor if you have ever had: tendon problems, bone problems, arthritis, or other joint problems; blood circulation problems, aneurysm, narrowing or hardening of the arteries ; heart problems, high blood pressure ; a genetic disease such as Marfan syndrome or Ehler's-Danlos syndrome; diabetes; a muscle or nerve disorder, such as myasthenia gravis ; liver or kidney disease; a seizure, head injury, or brain tumor; long QT syndrome (in you or a family member); or low levels of potassium in your blood (hypokalemia). Moxifloxacin is not approved for use by anyone younger than 18 years old. Tell your doctor if you are pregnant or breastfeeding.

Side Effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling). Moxifloxacin can cause serious side effects, including tendon problems, side effects on your nerves (which may cause permanent nerve damage), serious mood or behavior changes (after just one dose), or low blood sugar (which can lead to coma). Stop using moxifloxacin and call your doctor at once if you have: low blood sugar --headache, hunger, sweating, irritability, dizziness, nausea, fast heart rate , or feeling anxious or shaky; nerve symptoms in your hands, arms, legs, or feet --numbness, weakness, tingling, burning pain; serious mood or behavior changes --nervousness, confusion, agitation, paranoia, hallucinations, memory problems, trouble concentrating, thoughts of suicide; or signs of tendon rupture --sudden pain, swelling, bruising, tenderness, stiffness, movement problems, or a snapping or popping sound in any of your joints (rest the joint until you receive medical care or instructions). In rare cases, moxifloxacin may cause damage to your aorta, the main blood artery of the body. This could lead to dangerous bleeding or death. Get emergency medical help if you have severe and constant pain in your chest, stomach, or back. Also stop using moxifloxacin and call your doctor at once if you have: severe stomach pain, diarrhea that is watery or bloody; fast or pounding heartbeats, fluttering in your chest, shortness of breath , and sudden dizziness (like you might pass out); muscle weakness, breathing problems; a seizure (convulsions); any skin rash, no matter how mild; increased pressure inside the skull --severe headaches, ringing in your ears, vision problems, pain behind your eyes; or liver problems --upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Common side effects of moxifloxacin may include: nausea, diarrhea; dizziness; or headache. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Moxifloxacin can cause serious side effects, including tendon problems, nerve damage, serious mood or behavior changes, or low blood sugar. Stop using this medicine and call your doctor at once if you have symptoms such as: headache, hunger, irritability, numbness, tingling, burning pain, confusion, agitation, paranoia, problems with memory or concentration, thoughts of suicide, or sudden pain or movement problems in any of your joints. In rare cases, moxifloxacin may cause damage to your aorta, which could lead to dangerous bleeding or death. Get emergency medical help if you have severe and constant pain in your chest, stomach, or back.

High Risk Groups

Adult Dosage

400 mg (400 (400)) 24 hourly IV — Given over 60 minutes. 400 mg (400 (400)) 24 hourly PO — For 5-10 days in exacerbation of chronic bronchitis.

Child Dosage

No child dosage information is recorded for this medicine yet.

Neonatal Dosage

No neonatal dosage information is recorded for this medicine yet.

Drug Interactions

Some medicines can make moxifloxacin much less effective when taken at the same time. If you take any of the following medicines, take your moxifloxacin dose 4 hours before or 8 hours after you take the other medicine: the ulcer medicine sucralfate, or antacids that contain calcium, magnesium, or aluminum (such as Maalox, Milk of Magnesia , Mylanta, Pepcid Complete , Rolaids, Tums, and others); didanosine (Videx) powder or chewable tablets; lanthanum carbonate or sevelamer; or vitamin or mineral supplements that contain aluminum, iron, magnesium, or zinc. Tell your doctor about all your other medicines, especially: erythromycin ; a blood thinner (warfarin, Coumadin, Jantoven); a diuretic or "water pill"; heart rhythm medication; insulin or oral diabetes medicine (check your blood sugar regularly); medicine to treat depression or mental illness; steroid medicine (such as prednisone); or NSAIDs (nonsteroidal anti-inflammatory drugs) --aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin , meloxicam, and others. This list is not complete. Other drugs may affect moxifloxacin, including prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible drug interactions are listed here.

Storage

Store Below 30°C. Refrigeration and Freezing is not recommended.

Available Brands in Pakistan

144 active brands listed alphabetically.

Moxifloxacin

Available Brands in Pakistan

ACFLOX

ADMOX

AJIMOX

A-MOX

ARAMOX

ARBIMOX

ASPIMOX

ASTROMOX

ASTRON

AVELOX

BACTIMOX

BACTIROL

BARIMOX

BEMOX

BIOFLOXACIN

BIOMOX

B-QUIN

CAPMOX

CIMOX

CINMOX

DEVIMOX

DURAMOX

EM-FLOX

ENGMOX

EYEMOX

EZEMOX

FLUXAQUIN

FOTIFLOX

GLIMOX

G-MOX

GOLDSPEC

HARRIFLOX

HIRAMOX

INFU-MOX

INMEX

IZILON

LINZOX

LIXOM

LIXOM TABLET

LOCGIN

LOXELIVE

MAFLEX

MAROXI

MAXLOX

MEFEE

MEFLOX

MEGAMOX

MERIFLOX

MFC-400

M-FLOXSEL

MFX

MICROCID

MIONEX

MOB

MOBIK

MOFEST

MOFILOX

MOFLAXA

MOFLOXEN

MOFOXIN

MOGIZ

MOKSI

MOLINZA

MOLOX

MOMAX

MONG

MOX

MOXAPT

MOXARA

MOXBAY

MOXBAY

MOXBEC

MOXDAN

MOXER

MOXI

MOXIBACT

MOXICIN

MOXICURE