Muromonab-cd3

Muromonab-CD3 is a monoclonal antibody. It is used to reduce the body's natural immunity in patients who receive organ (for example, kidney) transplants. When a patient receives an organ transplant, the body's white blood cells will try to get rid of (reject) the transplanted organ. Muromonab-CD3 works by preventing the white blood cells from doing this. The effect of muromonab-CD3 on the white blood cells may also reduce the body's ability to fight infections. Before you begin treatment, you and your doctor should talk about the good this medicine will do as well as the risks of using it. Muromonab-CD3 is to be administered only by or under the immediate supervision of your doctor.

Muromonab-CD3 is a monoclonal antibody. It is used to reduce the body's natural immunity in patients who receive organ (for example, kidney) transplants. When a patient receives an organ transplant, the body's white blood cells will try to get rid of (reject) the transplanted organ. Muromonab-CD3 works by preventing the white blood cells from doing this. The effect of muromonab-CD3 on the white blood cells may also reduce the body's ability to fight infections. Before you begin treatment, you and your doctor should talk about the good this medicine will do as well as the risks of using it. Muromonab-CD3 is to be administered only by or under the immediate supervision of your doctor.

Muromonab-cd3 is contraindicated in conditions like Hypertension,Fever,Hypersensitivity to the drug.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Because of the way that muromonab-CD3 acts on the body, there is a chance that it may cause effects that may not occur until years after the medicine is used. These delayed effects may include certain types of cancer, such as lymphomas and skin cancers. Discuss these possible effects with your doctor. Although not all of the following side effects may occur, if they do occur, they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Less common Chest pain rapid or irregular heartbeat shortness of breath or wheezing swelling of face or throat Check with your doctor as soon as possible if any of the following side effects occur: More common Diarrhea dizziness or faintness fever and chills general feeling of discomfort or illness headache muscle or joint pain nausea and vomiting Less common or rare Confusion black, tarry stools blood in urine or stools convulsions (seizures) cough or hoarseness hallucinations (seeing, hearing, or feeling things that are not there) itching or tingling loss of hearing or vision lower back or side pain painful or difficult urination pinpoint red spots on skin skin rash sores, ulcers, or white spots on the lips or in the mouth stiff neck swollen or painful glands tightness in the chest trembling and shaking of hands troubled breathing unusual sensitivity of eyes to light unusual bleeding or bruising unusual tiredness weakness After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects: Fever and chills Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Prescribing should be kept to a minimum in all patients with severe liver disease, especially if jaundice, ascites, or evidence of encephalopathy present. Patient temperature should not exceed 37.8°C (100°F) at time of administration. Severe pulmonary edema has occurred in patients with fluid overload. May result in an increased susceptibility to infection; dosage of concomitant immunosuppressants should be reduced during Muromonab-cd3 therapy; cyclosporine should be decreased to 50% usual maintenance dose and maintenance therapy resumed about 4 days before stopping Muromonab-cd3.

Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

5 mg (5 (5)) As recommended. IV — Once a day injected in vein for 10-14 days.

2.5 to 5 mg (3.8 (3.75)) As recommended. IV — IV Injection for 10-14 days due to higher CD3 lymphocytes count the dose required to be titrated upw

No neonatal dosage information is recorded for this medicine yet.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

No storage information is recorded for this medicine yet.