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Medicines/Generics/Nitrofurantoin

Nitrofurantoin

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview
Nitrofurantoin is an antibiotic that fights bacteria in the body. Nitrofurantoin is used to treat urinary tract infections . Nitrofurantoin may also be used for purposes not listed in this medication guide.
Indications
Nitrofurantoin is an antibiotic that fights bacteria in the body. Nitrofurantoin is used to treat urinary tract infections . Nitrofurantoin may also be used for purposes not listed in this medication guide.
Contraindications
You should not take nitrofurantoin if you are allergic to it, or if you have: severe kidney disease; a history of jaundice or liver problems caused by taking nitrofurantoin; if you are urinating less than usual or not at all; or if you are in the last 2 to 4 weeks of pregnancy. Do not take nitrofurantoin if you are in the last 2 to 4 weeks of pregnancy. To make sure nitrofurantoin is safe for you, tell your doctor if you have: kidney disease; anemia; diabetes; an electrolyte imbalance or vitamin B deficiency; glucose-6-phosphate dehydrogenase (G6PD) deficiency; or any type of debilitating disease. FDA pregnancy category B. This medicine is not expected to be harmful to an unborn baby during early pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Nitrofurantoin can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are taking this medicine. Nitrofurantoin should not be given to a child younger than 1 month old.
Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction to nitrofurantoin: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: diarrhea that is watery or bloody; sudden chest pain or discomfort, wheezing, dry cough or hack; new or worsening cough, trouble breathing; fever, chills, body aches, tiredness, unexplained weight loss; numbness, tingling, or pain in your hands or feet; liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or lupus-like syndrome--joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy skin color. Serious side effects may be more likely in older adults and those who are ill or debilitated. Common nitrofurantoin side effects may include: headache, dizziness; gas, upset stomach; mild diarrhea; or vaginal itching or discharge. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
You should not take nitrofurantoin if you have severe kidney disease, urination problems, or a history of jaundice or liver problems caused by nitrofurantoin. Do not take this medicine if you are in the last 2 to 4 weeks of pregnancy.
High Risk Groups
You should not take nitrofurantoin if you have severe kidney disease, urination problems, or a history of jaundice or liver problems caused by nitrofurantoin. Do not take this medicine if you are in the last 2 to 4 weeks of pregnancy.
Adult Dosage
0.714 to 1.428 mg/kg (1.1 (1.071)) 6 hourly PO — For 7 to 10 days with food or milk. Scraped Dose — Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Take nitrofurantoin with food. Shake the oral suspension (liquid) well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one. You may mix your liquid dose with water, milk, or fruit juice to make it easier to swallow. Drink the entire mixture right away. Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Nitrofurantoin will not treat a viral infection such as the common cold or flu. Nitrofurantoin is usually given for up to 3 to 7 days. If you use this medicine long-term, you may need frequent medical tests at your doctor's office. Nitrofurantoin can cause unusual results with certain lab tests for glucose (sugar) in the urine. Tell any doctor who treats you that you are using nitrofurantoin. Store at room temperature away from moisture, heat, and light.
Child Dosage
1 mg/kg (1 (1)) As recommended. Oral — For prophylactic treatment 3 mg/kg (3 (3)) 6 hourly Oral —
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
Other drugs may interact with nitrofurantoin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Storage
Tab Store in a well closed container. Protect from Sunlight.