Octreotide (Acetate)
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Octreotide is a man-made protein that is similar to a hormone in the body called somatostatin. Octreotide lowers many substances in the body such as insulin and glucagon (involved in regulating blood sugar), growth hormone, and chemicals that affect digestion.
Octreotide is used to treat acromegaly . Octreotide is also used to reduce flushing episodes and watery diarrhea caused by cancerous tumors ( carcinoid syndrome ) or tumors called vasoactive intestinal peptide tumors (VIPomas).
Octreotide may also be used for purposes not listed in this medication guide.
Indications
Octreotide is a man-made protein that is similar to a hormone in the body called somatostatin. Octreotide lowers many substances in the body such as insulin and glucagon (involved in regulating blood sugar), growth hormone, and chemicals that affect digestion.
Octreotide is used to treat acromegaly . Octreotide is also used to reduce flushing episodes and watery diarrhea caused by cancerous tumors ( carcinoid syndrome ) or tumors called vasoactive intestinal peptide tumors (VIPomas).
Octreotide may also be used for purposes not listed in this medication guide.
Contraindications
You should not use octreotide if you are allergic to it.
Tell your doctor if you have ever had:
diabetes; gallbladder disease ; heart disease , high blood pressure , or heart rhythm disorder; thyroid problems; pancreatitis ; liver disease ; or kidney disease (or if you are on dialysis).
Tell your doctor if you are pregnant or breastfeeding.
Using octreotide can affect certain hormones that may make it easier for you to get pregnant, even if you were unable to get pregnant before. Talk to your doctor about using birth control to avoid unwanted pregnancy.
Octreotide is not approved for use by anyone younger than 18 years old.
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Octreotide may cause serious side effects. Call your doctor at once if you have:
severe constipation ; slow or uneven heartbeats; signs of gallstones --fever, chills, nausea, vomiting, severe pain in your upper stomach spreading to your back, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); high blood sugar --increased thirst, increased urination, dry mouth, fruity breath odor; low blood sugar --headache, hunger, sweating, irritability, dizziness, fast heart rate , and feeling anxious or shaky; or underactive thyroid --extreme tired feeling, dry skin, joint pain or stiffness, muscle pain or weakness, hoarse voice, feeling more sensitive to cold temperatures, weight gain.
Common side effects of octreotide may include:
gallstones ; nausea, vomiting, diarrhea, stomach pain, gas; headache, back pain ; or dizziness, tiredness.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
High Risk Groups
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Adult Dosage
0.05 to 0.2 mg (0.12 (0.125)) 8 hourly SC —
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
Tell your doctor about all your other medicines, especially:
bromocriptine (Cycloset, Parlodel); cyclosporine ; insulin or oral diabetes medicine; or heart or blood pressure medication.
This list is not complete. Other drugs may affect octreotide, including prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible drug interactions are listed here.
Storage
Inj Store at room temperature or refrigerator. Do not Freeze. Protect from Sunlight. Use within 2 weeks if kept at room temperature.
Available Brands in Pakistan
5 active brands listed alphabetically.
ASTEROTIDE
ActiveHOFFMAN HEALTH PAKISTAN LTD.
DML: ASTEROTIDE
Inj
HATIDE
ActiveHYGEIA PHARMACEUTICALS
DML: HATIDE
Inj
JINTROTIDE
ActiveACCURATE MEDICAL SUPPLIERS
DML: JINTROTIDE
Inj
SANDOSTATIN
ActiveNOVARTIS PHARMA (PAK) LTD
DML: SANDOSTATIN
Inj
SANDOSTATIN LAR
ActiveNOVARTIS PHARMA (PAK) LTD
DML: SANDOSTATIN LAR
Inj
