Oxacillin
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Oxacillin is a penicillin antibiotic that fights bacteria in the body.
Oxacillin is used to treat many different types of infections caused by staphylococcus (also called "staph" infection).
Oxacillin may also be used for purposes not listed in this medication guide.
Indications
Oxacillin is a penicillin antibiotic that fights bacteria in the body.
Oxacillin is used to treat many different types of infections caused by staphylococcus (also called "staph" infection).
Oxacillin may also be used for purposes not listed in this medication guide.
Contraindications
You should not use this medicine if you are allergic to oxacillin or to any other penicillin antibiotic, such as:
amoxicillin , Augmentin; ampicillin ; carbenicillin; dicloxacillin ; or penicillin.
To make sure oxacillin is safe for you, tell your doctor if you have:
asthma; kidney disease; liver disease ; or a history of any type of allergy.
Oxacillin injection is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant.
Oxacillin can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.
Oxacillin can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hives, itching; wheezing, difficult breathing; feeling light-headed; swelling of your face, lips, tongue, or throat.
An allergic reaction to oxacillin can occur right after you use the medicine, or you may have a delayed reaction.
An immediate allergic reaction can occur within 48 hours after you use oxacillin, and may cause fever with an itchy skin rash.
A delayed reaction may occur past 48 hours and up to 4 weeks after you use oxacillin. Symptoms of a delayed reaction may include fever with swollen glands, rash or itching, joint pain , stomach pain, and a general ill feeling.
Call your doctor or seek medical attention if you think you may be having an allergic reaction. Also call your doctor at once if you have:
severe stomach pain, diarrhea that is watery or bloody; nausea, vomiting; bruising or swelling around the IV needle; kidney problems --little or no urination, painful or difficult urination, red or pink urine; liver problems --nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or low white blood cell counts --fever, chills, sore throat , swollen gums, mouth sores, pain when swallowing, skin sores, cold or flu symptoms, cough, trouble breathing.
Common side effects of oxacillin may include:
nausea, upset stomach , vomiting, mild diarrhea; vaginal itching or discharge; swollen, black, or "hairy" tongue; or thrush (white patches or inside your mouth or throat).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
You should not use oxacillin if you are allergic to oxacillin or to any other penicillin antibiotic.
High Risk Groups
You should not use oxacillin if you are allergic to oxacillin or to any other penicillin antibiotic.
Adult Dosage
1 g (1 (1)) 6 hourly IV — For severe infections: should be given every 4-6 hrs.
250 to 500 mg (380 (375)) 6 hourly IV — For mild to moderate infections: should be given every 4-6 hrs.
Child Dosage
12.5 mg/kg (12 (12.5)) 6 hourly IV or IM — For children less then 40kg. 100mg/kg/day can be given in severe infections.
500 to 250 mg (380 (375)) 6 hourly IV or IM — For children weighing 40kg 1g every 4 to 6 hrs can be given in severe infections.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Tell your doctor about all your current medicines and any you start or stop using, especially:
probenecid ; or tetracycline .
This list is not complete. Other drugs may interact with oxacillin, including prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible interactions are listed in this medication guide.
Storage
Cap Store in a well closed container, at room temperature. IM Inj (after reconstituted) Store at room temperature, Below 20°C or in refrigerator. Use within 7 days if refrigerated and within 3 days if kept at room temperature. Oral Soln (reconstituted) Store at room temperature or refrigerator. Do not Freeze. Use within 2 weeks if refrigerated and within 3 days if kept at room temperature.
Available Brands in Pakistan
No brands are recorded for this generic.
