Oxethazaine
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Oxethazaine is amide anesthetic, with a prolong duration of action. Oxethazaine is designated as N,N-bis-(N-methyl-N-phenyl-butyl-acetamide)-betahydroxyethylamine. Oxethazaine is given by mouth along with antacid for the symptomatic relief of gastro-esophageal reflux disease. Oxethazaine is also used in the ointments and suppositories for the relief of pain associated with hemorrhoids.
Indications
Oxethazaine is primarily indicated in conditions like Esophagitis, Reflux esophagitis, and can also be given in adjunctive therapy as an alternative drug of choice in Hemorrhoids.
Contraindications
Oxethazaine is contraindicated in conditions like Hypersensitivity to any component of product.
Side Effects
The signs and symptoms that are produced after the acute overdosage of Oxethazaine include Drowsiness, Dizziness, Fainting. The symptomatic adverse reactions produced by Oxethazaine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Pruritus, Hypersensitivity reactions, Glossitis, Idiosyncratic rashes.
Warnings
The use of magnesium-containing antacids in patients with mild to moderate renal impairment should be carefully monitored due to a possible increased danger of hypermagnesemia. Hypophosphatemia may occur with prolonged administration or large doses of aluminum-containing antacids (except aluminum phosphate) especially in patients with an inadequate dietary intake of phosphorus.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
5 to 10 mg (7.5 (7.5)) 8 hourly PO —
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
No data regarding the interactions of Oxethazaine was found.
Storage
Tab Protect from Sunlight and Heat.
Available Brands in Pakistan
No active brands are currently recorded for this generic.
4 records are present but flagged "Unverified / Legacy" and excluded.