Oxprenolol (HCl)
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Oxprenolol (HCl) is a non-selective ß receptor blocking agent with some partial agonist activity. Chemically Oxprenolol (HCl) is 1-[2-(allyloxy) phenoxy]-3-isopropylaminopropane-2-ol hydrochloride. Oxprenolol (HCl) is antihypertensive agent and used in the management of hypertension, angina pectoris, also in anxiety disorders.
Indications
Oxprenolol (HCl) is primarily indicated in conditions like Angina, Cardiac arrhythmia, Hypertension, Obstructive cardiomyopathy, To prevent 1st occurrence of neural tube defect, To prevent recurrence of neural tube defect, and can also be given in adjunctive therapy as an alternative drug of choice in Anxiety.
Contraindications
Oxprenolol (HCl) is contraindicated in conditions like Bronchospasm, Cardiac failure, Hemorrhage, Bradycardia, Low cardiac output.
Side Effects
Oxprenolol (HCl) produces potentially life-threatening effects which include Bradycardia, Hypoglycemia, Hypotension, Bronchospasm. which are responsible for the discontinuation of Oxprenolol (HCl) therapy.The symptomatic adverse reactions produced by Oxprenolol (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Lethargy, Wheezing, Coolness of extremities.
Warnings
Oxprenolol should be used with caution in diabetic patients or patients with liver or kidney impairments.
High Risk Groups
Drug should not be given to Paediatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
0.285 to 2.285 mg/kg (1.3 (1.285)) 8 hourly PO — -
Child Dosage
1 mg/kg (1 (1)) 8 hourly Oral — -
Neonatal Dosage
1 mg/kg (1 (1)) 8 hourly Oral — -
Drug Interactions
Oxprenolol (HCl) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAdrenalineClonidine (HCl)Ergometrine (Maleate)simultaneous use of ergometrine and b- adrenoceptor blocker may increase peripheral vascular resistance. increase risk of vascular occlusion . simultaneous use of ergometrine and b- adrenoceptor blocker should be avoidedHydralazine (HCl)IndomethacinLignocaineVerapamil (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tab
Available Brands in Pakistan
No brands are recorded for this generic.