Oxymetazoline (HCl)
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Oxymetazoline (HCl) is a sympathomimetic amine of the imidazoline class. Oxymetazoline (HCl) is a direct agonist at alpha-adrenergic receptors with no action on beta-adrenergic receptors. Oxymetazoline (HCl) is used as a nasal decongestant in allergic rhinitis, and also as a ocular decongestant in allergic conjunctivitis (whether seasonal or perennial). Chemically Oxymetazoline (HCl) is 3-[(4,5-dihydro-1H-imidazol-2-yl) methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol hydrochloride. Oxymetazoline (HCl) is available for nasal and ophthalmic administration.
Indications
Oxymetazoline (HCl) is primarily indicated in conditions like Ocular congestion, Otitis media, Rhinitis, Sinusitis, and can also be given in adjunctive therapy as an alternative drug of choice in Conjunctivitis.
Contraindications
Oxymetazoline (HCl) is contraindicated in conditions like Narrow-angle glaucoma.
Side Effects
The severe or irreversible adverse effects of Oxymetazoline (HCl), which give rise to further complications include Rhinitis medicamentosa. The signs and symptoms that are produced after the acute overdosage of Oxymetazoline (HCl) include Hypotension, Sedation. The symptomatic adverse reactions produced by Oxymetazoline (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Stinging on application, Dryness of eye.
Warnings
Use topical decongestant (oxymetazoline) only in acute conditions, not longer than 3 to 5 days. It should be use sparingly in all patients, especially in infants, children and in cardiac patients.
High Risk Groups
Drug should not be given to Pediatrics, Pregnant Mothers, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
0.025 % (0.025 (0.025)) As recommended. Ophthalmic — drops
0.09 % (0.09 (0.09)) 12 hourly Intra Nasal — 1-2 drops in each nostril.
Child Dosage
0.025 to 0.035 mg (0.03 (0.03)) 12 hourly Nasal — For children above 5 yrs.
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
No data regarding the interactions of Oxymetazoline (HCl) was found.
Storage
Nasal Spray, Nasal Drops Store Below 40°C. Protect from Sunlight and Heat.
Available Brands in Pakistan
1 active brand listed alphabetically.
OXYLIN EYE DROPS
ActiveBARRETT HODGSON PAKISTAN (PVT) LTD.
DML: OXYLIN EYE DROPS
Eye Drops
1 additional record is present but flagged "Unverified / Legacy" and not listed.