Papaveretum
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Papaveretum is a narcotic analgesic. Since 1993, papaveretum has been defined in the British Pharmacopoeia (BP) as a mixture of 253 parts morphine hydrochloride, 23 parts papaverine hydrochloride, and 20 parts codeine hydrochloride. Its action is predominantly the result of its morphine content. It relieves moderate to severe pain. It also suppresses cough and produces feeling of well being. Papaveretum is administered parenterally.
Indications
Papaveretum is primarily indicated in conditions like Pain, and can also be given in adjunctive therapy as an alternative drug of choice in Surgery.
Contraindications
Papaveretum is contraindicated in conditions like Renal diseases, Respiratory disease, Hepatic disease.
Side Effects
Papaveretum produces potentially life-threatening effects which include Respiratory depression. which are responsible for the discontinuation of Papaveretum therapy. The signs and symptoms that are produced after the acute overdosage of Papaveretum include Bradycardia, Cardiac arrest, Cyanosis. The symptomatic adverse reactions produced by Papaveretum are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea and vomiting.
Warnings
Initial dose should be reduced in elderly, patient of hepatic, pulmonary or renal function, myxedema or hypothyroidism, central nervous system depression or coma, prostatic hypertrophy and gall bladder.
High Risk Groups
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, Geriatrics, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
0.142 to 0.285 mg/kg (0.21 (0.2135)) As recommended. IM — As Required
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Papaveretum is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholCarbamazepineCimetidine (HCl)Dexamphetamine (Sulphate)EtomidateHydroxyzine These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Inj Protect from Sunlight.
Available Brands in Pakistan
No brands are recorded for this generic.