Para-Amino Salicylic Acid
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Para-Amino Salicylic Acid is used in combination for the treatment of tuberculosis, when other more potent drugs cannot be used.
Indications
Para-Amino Salicylic Acid is primarily indicated in conditions like Multi-drug resistance tuberculosis.
Contraindications
Para-Amino Salicylic Acid is contraindicated in conditions like Renal diseases, Hypersensitivity.
Side Effects
The severe or irreversible adverse effects of Para-Amino Salicylic Acid, which give rise to further complications include Rashes, Fever, Hepatotoxicity, Conjunctivitis, Eosinophilia, Pruritus, Hypersensitivity reactions, Pulmonary infiltration. Para-Amino Salicylic Acid produces potentially life-threatening effects which include Hepatotoxicity, Necrosis, Fatty vacuolization, Granular degeneration. which are responsible for the discontinuation of Para-Amino Salicylic Acid therapy. The symptomatic adverse reactions produced by Para-Amino Salicylic Acid are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Anorexia, Diarrhea, Abdominal cramps, GI upset, Goiter, Macrocytic anemia.
Warnings
No warnings information is recorded for this medicine yet.
High Risk Groups
Drug should not be given to Pediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, and patients suffering from Kidney dysfunction. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
10 to 12 g (11 (11)) As recommended. PO — Daily in 2-3 div.doses
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Para-Amino Salicylic Acid is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementProbenecidRifabutinRifampicin These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tab Store in a well closed container, at room temperature, Below 30°C. Protect from Sunlight.
Available Brands in Pakistan
1 active brand listed alphabetically.
P.A.S
ActiveSTAR LABORATORIES (PVT) LTD.
DML: P.A.S
Tabs