Para Aminobenzoic Acid
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Synera patches contain a combination of lidocaine and tetracaine . Lidocaine and tetracaine are local anesthetics (numbing medicines). They work by blocking nerve signals in your body.
Synera patches are used to numb a small area of your skin. This can help prevent pain during certain medical procedures such as a skin biopsy, minor skin surgery, insertion of an intravenous (IV) needle, or other needle-stick procedures.
Synera patches are also used to numb a skin area during minor cosmetic procedures such as a Botox injection, laser treatment, or tattoo removal.
Indications
Synera patches contain a combination of lidocaine and tetracaine . Lidocaine and tetracaine are local anesthetics (numbing medicines). They work by blocking nerve signals in your body.
Synera patches are used to numb a small area of your skin. This can help prevent pain during certain medical procedures such as a skin biopsy, minor skin surgery, insertion of an intravenous (IV) needle, or other needle-stick procedures.
Synera patches are also used to numb a skin area during minor cosmetic procedures such as a Botox injection, laser treatment, or tattoo removal.
Contraindications
You should not use Synera if you are allergic to:
any type of numbing medicine; or sunscreen or other skin products that contain para-aminobenzoic acid (PABA).
Fatal overdoses have occurred when numbing medicines were used without the advice of a medical doctor (such as during a cosmetic procedure like laser hair removal). Be aware that many cosmetic procedures are performed without a medical doctor present.
Synera skin patches are not approved for use by anyone younger than 18 years old.
To make sure Synera is safe for you, tell your doctor if you have:
liver disease; a blood cell disorder called methemoglobinemia (in you or a family member); a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency; a condition for which you take a heart rhythm medicine; or allergy to any other medicine used for anesthesia.
Older adults and people who are debilitated may be more sensitive to the effects of this medicine.
Tell your doctor if you are pregnant or breastfeeding.
If you apply lidocaine and tetracaine topical to your chest, avoid areas that may come into contact with the baby's mouth.
The Synera transdermal patch may burn your skin if you wear the patch during an MRI (magnetic resonance imaging). Remove the patch before undergoing such a test.
Side Effects
Get emergency medical help if you have signs of an allergic reaction to Synera: hives ; wheezing, difficulty breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers or call your doctor right away if you have:
severe burning, stinging, or other irritation where the medicine was applied; sudden dizziness or drowsiness after the medicine is applied; pale, gray, or blue colored skin; headache , fast heartbeats, shortness of breath; tiredness, or feeling like you might pass out; blurred vision, ringing in your ears; or unusual sensations of hot or cold.
Common Synera side effects include:
skin redness; skin swelling; or changes in skin color where the medicine was applied.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
An overdose of numbing medicine can cause fatal side effects if too much of the medicine is absorbed through your skin. This can happen if you apply more than the recommended dose, or if you leave a Synera skin patch on too long.
Keep both used and unused Synera skin patches out of the reach of children or pets.
High Risk Groups
An overdose of numbing medicine can cause fatal side effects if too much of the medicine is absorbed through your skin. This can happen if you apply more than the recommended dose, or if you leave a Synera skin patch on too long.
Keep both used and unused Synera skin patches out of the reach of children or pets.
Adult Dosage
300 to 400 mg/day (350 (350)) As recommended. PO —
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Medicine used on the skin is not likely to be affected by other drugs you use. However, some drugs can cause conditions that may make it harmful for you to use Synera. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins , and herbal products .
Storage
Gel, Topical Soln Store in a well closed container. Protect from Sunlight.
Available Brands in Pakistan
No brands are recorded for this generic.