Medicines/Generics/Pefloxacin

Pefloxacin

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview

Pefloxacin is a fluoroquinolone antibiotic with actions and uses similar to those of ciprofloxacin. Pefloxacin is used to treat a variety of bacterial infections like respiratory tract, ENT, skin, urinary tract infections etc. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the drug at regular intervals of time throughout the day and night as prescribed. Pefloxacin is important to take the drug for the full time period as prescribed. Discontinuation of the drug, may result in ineffective treatment.

Indications

Pefloxacin is primarily indicated in conditions like Acne, Bacterial infections, Bronchitis, Burns, Conjunctivitis, Cystitis, Dysenteries, Folliculitis, Impetigo, Otitis media, Pneumonia, Prostatitis, Pyelonephritis, Respiratory tract infections, Sedation in intensive care, Sinusitis, Superficial infections, Surgical infections, Tonsillitis, Urethritis.

Contraindications

Pefloxacin is contraindicated in conditions like Hypersensitivity.

Side Effects

The symptomatic adverse reactions produced by Pefloxacin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Insomnia, GI upset, Muscle pain, Articular pain.

Warnings

Adjust doses in the renal and hepatic impairment. Ask patients to report any signs of depression.

High Risk Groups

Drug should not be given to Pediatrics, and Pregnant Mothers. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Adult Dosage

400 mg (400 (400)) 12 hourly IV Inf — Over 60 min. 400 mg (400 (400)) 12 hourly PO —

Child Dosage

( ) — Not recommended in this age group

Neonatal Dosage

( ) — Not recommended in this age group

Drug Interactions

No data regarding the interactions of Pefloxacin was found.

Storage

Tab, Inj Protect from Sunlight.