Pegloticase
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Pegloticase is used to treat chronic gout. Pegloticase is usually given after other gout medications have been tried without successful treatment of symptoms.
Pegloticase may also be used for purposes not listed in this medication guide.
Indications
Pegloticase is used to treat chronic gout. Pegloticase is usually given after other gout medications have been tried without successful treatment of symptoms.
Pegloticase may also be used for purposes not listed in this medication guide.
Contraindications
You should not use pegloticase if you are allergic to it, or if you have a genetic enzyme deficiency called glucose -6-phosphate dehydrogenase (G6PD) deficiency.
Some medicines can cause unwanted or dangerous effects when used with pegloticase. Your doctor may change your treatment plan if you also use:
allopurinol ( Zyloprim ); or febuxostat (Uloric).
Tell your doctor if you have ever had:
heart problems; or high blood pressure .
It is not known whether pegloticase will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your caregiver if you feel nervous, light-headed, itchy, short of breath, or have fast heartbeats, chest discomfort, or redness of your skin during the injection.
Pegloticase may cause serious side effects. Call your doctor at once if you have:
chest pain; or flushing (warmth, redness, or tingly feeling).
Common side effects of pegloticase may include:
COVID-19 symptoms such as fever or chills, cough, sore throat , shortness of breath , fatigue, muscle or body aches, headache , loss of taste or smell; hives, shortness of breath, chest pain or discomfort, skin redness, or itching; joint pain ; allergic reactions ; new gout flares ; nausea, vomiting , constipation ; or bruising.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.
Tell your caregivers right away if you feel itchy, light-headed, short of breath, or have chest discomfort or skin redness during the injection.
High Risk Groups
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.
Tell your caregivers right away if you feel itchy, light-headed, short of breath, or have chest discomfort or skin redness during the injection.
Adult Dosage
8 to 8 mg (8 (8)) As recommended. IV — Pegloticase should be administered Every 2 weeks.
Dilute solution Pegloticase to reach Room Temperature.
Donot institute Pegloticase therapy with oral urate lowering agents.
donot Administer as IV push or Bolus
Administer IV infusion over no less than 120minutes via gravity feed, syringe type pump or infusion pump
Monitor serum Uric Acid Level
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Other drugs may affect pegloticase, including prescription and over-the-counter medicines, vitamins , and herbal products . Tell your doctor about all your current medicines and any medicine you start or stop using.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No brands are recorded for this generic.