Pemetrexed
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Pemetrexed is used in adults to treat a certain type of lung cancer that has returned or has spread to other parts of the body (metastatic).
Pemetrexed is also used to treat a type of cancer that affects the lining of the lungs in adults who cannot have surgery .
Pemetrexed may be used in combination with other cancer medicines.
Pemetrexed may also be used for purposes not listed in this medication guide.
Indications
Pemetrexed is used in adults to treat a certain type of lung cancer that has returned or has spread to other parts of the body (metastatic).
Pemetrexed is also used to treat a type of cancer that affects the lining of the lungs in adults who cannot have surgery .
Pemetrexed may be used in combination with other cancer medicines.
Pemetrexed may also be used for purposes not listed in this medication guide.
Contraindications
You should not be treated with pemetrexed if you are allergic to it.
Tell your doctor if you have ever had:
bone marrow suppression; radiation treatment; or kidney disease.
Pemetrexed can harm an unborn baby if the mother or the father is using pemetrexed.
If you are a woman, you may need a pregnancy test to make sure you are not pregnant. Use birth control while using this medicine and for at least 6 months after your last dose. Tell your doctor if you become pregnant. If you are a man, use birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose. Tell your doctor right away if a pregnancy occurs.
It may be harder for you to get a woman pregnant while you are using this medicine. You should still use birth control to prevent pregnancy because the medicine can harm an unborn baby.
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
Side Effects
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat , burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Pemetrexed may cause serious side effects. Call your doctor at once if you have:
kidney problems --swelling, urinating less, feeling tired or short of breath; lung problems -- new or worsening cough, trouble breathing; low blood cell counts --fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; swelling, redness, or blistering of skin that was treated with radiation in the past; or new signs of infection (fever, weakness, cough, diarrhea , burning when you urinate).
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common side effects of pemetrexed may include:
tiredness, feeling short of breath, cough; swelling or sores in mouth, sore throat; fever, rash; low blood cell count; loss of appetite; or nausea , vomiting , diarrhea, constipation .
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.
High Risk Groups
Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.
Adult Dosage
500 mg/m2 (500 (500)) As recommended. IV — Pemetrexed is given in the form of Pemetrexed disodium infused over 10 min on day 1 of each 21-day cycle.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Pemetrexed can harm your kidneys, especially if you also use certain medicines for pain or arthritis (including ibuprofen, Advil, Motrin, and Aleve).
Other drugs may affect pemetrexed, including prescription and over-the-counter medicines, vitamins , and herbal products . Tell your doctor about all other medicines you use.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No active brands are currently recorded for this generic.
2 records are present but flagged "Unverified / Legacy" and excluded.