Pentostatin
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Pentostatin is used to treat hairy cell leukemia (a type of blood cancer).
Pentostatin may also be used for purposes not listed in this medication guide.
Indications
Pentostatin is used to treat hairy cell leukemia (a type of blood cancer).
Pentostatin may also be used for purposes not listed in this medication guide.
Contraindications
You should not use pentostatin if you are allergic to it.
Tell your doctor if you have ever had:
kidney disease; liver disease ; lung disease; any type of infection (including pneumonia ); or weak immune system (caused by disease or by using certain medicines).
Pentostatin may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.
You should not breastfeed while using pentostatin.
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Pentostatin may cause serious side effects. Call your doctor at once if you have:
skin sores, severe skin rash; confusion, hallucinations, problems with speech or memory, seizure; muscle twitching , loss of movement in any part of your body; numbness, tingling, or burning pain; fluid build-up in or around the lungs --pain when you breathe, feeling short of breath while lying down, wheezing, gasping for breath, cough with foamy mucus, cold, clammy skin, anxiety, rapid heartbeats; kidney problems --little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or low blood cell counts --fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.
Common side effects of pentostatin may include:
loss of appetite, nausea, vomiting, stomach pain; diarrhea; rash, itching; muscle pain ; headache, tiredness; or fever, chills, cough.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Pentostatin can cause harmful side effects on your kidneys, liver, lungs, or central nervous system. Call your doctor at once if you have symptoms such as: swelling, rapid weight gain, little or no urinating, pink or red urine, severe shortness of breath , wheezing, chest pain, cough, vision problems, numbness, tingling, or burning pain.
High Risk Groups
Pentostatin can cause harmful side effects on your kidneys, liver, lungs, or central nervous system. Call your doctor at once if you have symptoms such as: swelling, rapid weight gain, little or no urinating, pink or red urine, severe shortness of breath , wheezing, chest pain, cough, vision problems, numbness, tingling, or burning pain.
Adult Dosage
4 mg/m2 (4 (4)) As recommended. IV — Antiemetic should be given for 48-74 hours after pentostatin administration.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Tell your doctor about all your other medicines, especially:
carmustine ; cyclophosphamide ; etoposide ; fludarabine ; or vidarabine .
This list is not complete. Other drugs may affect pentostatin, including prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible drug interactions are listed here.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No brands are recorded for this generic.