Perazine Dimalonate
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Perazine dimalonate is a phenothiazine with general properties similar to those of chlorpromazine and is used for the treatment of psychotic conditions. It has a piperazine side-chain.
Indications
Perazine Dimalonate is primarily indicated in conditions like Psychotic illness.
Contraindications
Perazine Dimalonate is contraindicated in conditions like Coma,CNS depression,Hypersensitivity to any component of product.
Side Effects
The severe or irreversible adverse effects of Perazine Dimalonate, which give rise to further complications include Convulsions, Tachycardia, Cardiac arrhythmias, Anemia, Urticaria, Anemia, Hypotension, Tardive dyskinesia, Jaundice, Amenorrhea, Akathisia, Neuroleptic malignant syndrome, Anemia, Galactorrhea.The signs and symptoms that are produced after the acute overdosage of Perazine Dimalonate include Acute axonal neuropathies.The symptomatic adverse reactions produced by Perazine Dimalonate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Constipation, Dry mouth, Blurred vision, Weight gain, Miosis.
Warnings
Should be used with caution or not at all in patients with impaired liver, kidney, cardiovascular, cerebrovascular, and respiratory function and in those with angle-closure glaucoma, a history of jaundice, parkinsonism, diabetes mellitus, hypothyroidism, myasthenia gravis, paralytic ileus, prostatic hyperplasia, or urinary retention. Care is required in patients with epilepsy or a history of seizures as phenothiazines may lower the seizure threshold. Debilitated patients may be more prone to the adverse effects of phenothiazines as may the elderly, especially those with dementia. The sedative effects are most marked in the first few days of treatment; affected patients should not drive or operate machinery. Effects on the vomiting centre may mask the symptoms of overdosage of other drugs, or of disorders such as gastrointestinal obstruction. Use at extremes of temperature may be hazardous since body temperature regulation is impaired by phenothiazines. Should be used with caution in the presence of acute infection or leucopenia. Blood counts are advised if the patient develops an unexplained infection or fever.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
No adult dosage information is recorded for this medicine yet.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Perazine Dimalonate was found.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No brands are recorded for this generic.