Pericyazine
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Pericyazine is a phenothiazine derivative with actions, uses and general properties similar to those of chlorpromazine. Pericyazine is used in the treatment of various psychotic disorders including schizophrenia and disturbed behavior. Pericyazine is also used in severe anxiety.
Indications
Pericyazine is primarily indicated in conditions like Psychosis, Schizophrenia, Schizophrenia and other psychoses, Short-term adjunctive management of severe anxiety, Ulcerative colitis and crohn's disease, and can also be given in adjunctive therapy as an alternative drug of choice in Analgesia, Maintenance of light anaesthesia.
Contraindications
Pericyazine is contraindicated in conditions like Pheochromocytoma, Pregnancy, CNS depression, Comatose states, Breast feeding.
Side Effects
The symptomatic adverse reactions produced by Pericyazine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Excitement, Constipation, Insomnia, Dry mouth, Blurred vision, Rashes, Confusion, Sedation, Photosensitivity, Impotence, Hypotension, Weight gain, Apathy, Nasal congestion, Gynecomastia, Respiratory depression, Galactorrhea, Convulsions, GI disturbance, Extra pyramidal symptoms, Difficulty in micturition, Menstrual disturbances, Corneal and lens opacities, Purplish pigmentation of skin, cornea, conjunctiva, and retina.
Warnings
Antipsychotic (e.g. Pericyazine) should be used with caution in patients with hepatic impairment (can precipitate coma), renal impairment (start with small doses), cardiovascular disease, Parkinson`s disease (may be exacerbated by antipsychotics), epilepsy (and conditions predisposing to epilepsy), depression, myasthenia gravis, prostatic hypertrophy, or a personal or family history of angle-closure glaucoma (avoid pericyazine in these condition). Caution is also required in severe respiratory disease and in a patient with history of jaundice or who have blood dyscrasias (perform blood counts if unexplained infection or fever develops). Antipsychotic should be used with caution in the elderly, who are particularly susceptible to postural hypotension or to hyper or hypothermia in very hot or cold weather. Serious consideration should be given before prescribing these drugs for elderly patients. As photosensitization may occur with higher dosages, patients should avoid direct sunlight. DRIVING: Drowsiness may affect performance of skilled tasks (e.g. driving or operating machinery), especially at start of treatment; effects of alcohol are enhanced. WITHDRAWL: Withdrawal of antipsychotic drugs after long-term therapy should always be gradual and closely monitored to avoid the risk of acute withdrawal syndrome or rapid relapse.
High Risk Groups
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
10 to 40 mg (25 (25)) As recommended. PO — Dose to be taken in the evening. For maintenance therapy, the dosage should be reduced to the minimum effective dose. Lower doses of 2.5 to 15 mg in the morning, and 5 to 30 mg in the evening have been suggested.
5 to 20 mg (12 (12.5)) As recommended. PO — Dose to be taken in the morning.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Pericyazine was found.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No brands are recorded for this generic.