Phenindione

Cangrelor injection is used in patients undergoing percutaneous coronary intervention (PCI) to lower the risk of blood clots and heart attack. A heart attack or stroke may occur when a blood vessel in the heart or brain is blocked by a blood clot. Cangrelor reduces the chance that a harmful blood clot will form by preventing certain cells in the blood from clumping together. This effect of cangrelor may also increase the chance of serious bleeding in some people. This medicine is to be given only by or under the supervision of your doctor.

Cangrelor injection is used in patients undergoing percutaneous coronary intervention (PCI) to lower the risk of blood clots and heart attack. A heart attack or stroke may occur when a blood vessel in the heart or brain is blocked by a blood clot. Cangrelor reduces the chance that a harmful blood clot will form by preventing certain cells in the blood from clumping together. This effect of cangrelor may also increase the chance of serious bleeding in some people. This medicine is to be given only by or under the supervision of your doctor.

Phenindione

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur: More common Abdominal or stomach pain or swelling back pain black, tarry stools blood in the eyes blood in the urine bruising or purple areas on the skin coughing up blood decreased alertness dizziness headache joint pain or swelling nosebleeds Less common Difficult or labored breathing tightness in the chest Rare Cough difficulty with swallowing fast heartbeat hives, itching, or rash large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs noisy breathing puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue unusual tiredness or weakness Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Phenindione should be used with caution in patients with ulcers, unusual menstrual periods, diabetes, liver or kidney disease, high blood pressure, arthritis, thyroid problems, all recent infections, if have had recent surgery or of drug and food allergies. If patient have an illness that causes vomiting, diarrhea or fever for more than a few days, contact the doctor as these problems can change the effect of drug. Limit consumption of alcoholic beverages. Avoid sudden changes in dietary habits. Avoid ingesting unusual increases or decreases of foods high in Vitamin K (e.g. liver, cauliflower, cabbage, spinach and other green leafy vegetables, green tea, certain vegetables, cheeses and certain vitamin supplements). It is best to avoid strictly vegetarian diets that consist of foods high in vitamin K. Be extra careful to avoid injuries, because this medication can cause heavy bleeding. Be careful while brushing teeth and use an electric razor. It should not be used during pregnancy or lactation.

Drug should not be given to Pediatrics, Pregnant Mothers, Geriatrics, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

0.714 to 2.142 mg/kg (1.4 (1.428)) As recommended. PO — Maintenance, as required 1.428 to 2.857 mg/kg (2.1 (2.1425)) As recommended. PO — Initial,for first 2 days

1 to 3 mg/kg (2 (2)) 24 hourly Oral — -

1 to 3 mg/kg (2 (2)) 24 hourly Oral — -

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Abrocitinib Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Aceclofenac Acemetacin Amtolmetin Guacil Apixaban Argatroban Betrixaban Bivalirudin Bromfenac Bufexamac Caplacizumab-yhdp Celecoxib Choline Salicylate Citalopram Clonixin Clopidogrel Dabigatran Etexilate Danaparoid Desirudin Desvenlafaxine Dexibuprofen Dexketoprofen Diclofenac Diflunisal Dipyrone Droxicam Duloxetine Edoxaban Escitalopram Etodolac Etofenamate Etoricoxib Felbinac Fenoprofen Fepradinol Feprazone Floctafenine Flufenamic Acid Fluoxetine Flurbiprofen Fluvoxamine Fondaparinux Heparin Ibuprofen Indomethacin Ketoprofen Ketorolac Lepirudin Levomilnacipran Lornoxicam Loxoprofen Lumiracoxib Meclofenamate Mefenamic Acid Meloxicam Milnacipran Morniflumate Nabumetone Naproxen Nepafenac Niflumic Acid Nimesulide Nimesulide Beta Cyclodextrin Oxaprozin Oxyphenbutazone Parecoxib Paroxetine Phenindione Phenprocoumon Phenylbutazone Piketoprofen Piroxicam Prasugrel Proglumetacin Propyphenazone Proquazone Protein C Rivaroxaban Rofecoxib Salicylic Acid Salsalate Sertraline Sodium Salicylate Sulindac Tenoxicam Tiaprofenic Acid Tolfenamic Acid Tolmetin Valdecoxib Vilazodone Vortioxetine Warfarin

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