Medicines/Generics/Phenoxymethylpenicillin (K)

Phenoxymethylpenicillin (K)

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview

Phenoxymethylpenicillin (K) is acid-resistant penicillin used orally. The actions, uses and adverse effects similar to that of benzylpenicillin. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the drug at regular intervals of time throughout the day and night as prescribed. Phenoxymethylpenicillin (K) is important to take the drug for the full time period as prescribed. If you discontinue the drug it may result in ineffective treatment.

Indications

Phenoxymethylpenicillin (K) is primarily indicated in conditions like Bacterial infections, Endocarditis, Prophylaxis of rheumatic fever, Pruritus, Reversal of opioid-induced respiratory depression, Tonsillitis, Tonsillitis, otitis media.

Contraindications

Phenoxymethylpenicillin (K) is contraindicated in conditions like Penicillin hypersensitivity.

Side Effects

The severe or irreversible adverse effects of Phenoxymethylpenicillin (K), which give rise to further complications include Liver damage. Phenoxymethylpenicillin (K) produces potentially life-threatening effects which include Anaphylactic shock, Allergic reactions. which are responsible for the discontinuation of Phenoxymethylpenicillin (K) therapy. The symptomatic adverse reactions produced by Phenoxymethylpenicillin (K) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Diarrhea, Increased capillary fragility, Abdominal discomfort.

Warnings

History of allergy, renal impairment.

High Risk Groups

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Adult Dosage

250 to 500 mg (380 (375)) 6 hourly PO — As Required

Child Dosage

12.5 mg/kg (12 (12.5)) 6 hourly Oral — -

Neonatal Dosage

7.812 mg/kg (7.8 (7.812)) 6 hourly Intramuscular —

Drug Interactions

Phenoxymethylpenicillin (K) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAspirinCalamineMagnesium Oxides and HydroxidesNeomycinParomomycin (Sulphate)Zinc Oxide These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Storage

Tab, Syrup Store Below 40°C.