Phenprocoumon
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Phenprocoumon is an anticogulant functioning as Vit K antagonist.It is derivative of Coumarin.
Indications
Phenprocoumon is primarily indicated in conditions like Prophylaxis of recurrent haemorrhage, Thrombo-embolic complications, Venous thromboembolic disease, and can also be given in adjunctive therapy as an alternative drug of choice in Ischemic stroke prophylaxis.
Contraindications
Phenprocoumon is contraindicated in conditions like Blood dyscrasias,Pregnancy,Renal impairment.
Side Effects
The severe or irreversible adverse effects of Phenprocoumon, which give rise to further complications include Hemorrhage, Skin necrosis, Hematoma.The signs and symptoms that are produced after the acute overdosage of Phenprocoumon include Melena, Hematuria, Jaundice, Bleeding problems, Pancreatitis.The symptomatic adverse reactions produced by Phenprocoumon are more or less tolerable and if they become severe, they can be treated symptomatically, these include Alopecia, Diarrhea, Nausea and vomiting.
Warnings
Phenprocoumon should not be given to patients who are hemmorhagic. Dose alteration should be guided by regular monitoring of oral anticogulant therapy.
High Risk Groups
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
No adult dosage information is recorded for this medicine yet.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Phenprocoumon is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCholestyramineDue to enterohepatic cycling and the long half-life of phenprocoumon, an interaction between these two drugs could not be avoided. We therefore recommend that cholestyramine not be administered to patients treated with drugs undergoing enterohepatic cycling, such as oral anticoagulants.Metformin (HCl)Metformin increases elimination of phenprocoumon.Reviparin SodiumPhenprocoumon may potentiate the action of Reviparin. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No brands are recorded for this generic.