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Medicines/Generics/Piperazine

Piperazine

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview
Piperazine belongs to the family of medicines called anthelmintics. Anthelmintics are used in the treatment of worm infections. Piperazine is used to treat: common roundworms (ascariasis) and pinworms (enterobiasis; oxyuriasis). Piperazine works by paralyzing the worms. They are then passed in the stool. Piperazine is available only with your doctor's prescription.
Indications
Piperazine belongs to the family of medicines called anthelmintics. Anthelmintics are used in the treatment of worm infections. Piperazine is used to treat: common roundworms (ascariasis) and pinworms (enterobiasis; oxyuriasis). Piperazine works by paralyzing the worms. They are then passed in the stool. Piperazine is available only with your doctor's prescription.
Contraindications
Piperazine is contraindicated in conditions like Epilepsy, Impaired hepatic function, Impaired renal function.
Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Rare Blurring of vision clumsiness crawling or tingling feeling of the skin fever irregular, twisting movement, especially of the face, arms, and legs joint pain skin rash or itching Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Less common Abdominal or stomach cramps or pain diarrhea dizziness drowsiness headache muscle weakness nausea or vomiting tremors Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Chemical Class: Piperazine (class)
Warnings
The drug should be used with extreme caution in renal or hepatic impairment and in seizures.
High Risk Groups
Drug should not be given to Pediatrics, and Geriatrics. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
3 to 5 g (4 (4)) 24 hourly PO — For 2 days.
Child Dosage
100 mg/kg (100 (100)) 24 hourly Oral — Recommended for Ascariasis
Neonatal Dosage
100 mg/kg (100 (100)) 24 hourly Oral — Recommended for Ascariasis
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Duloxetine Epinephrine
Storage
syrup Store in a well closed container, Below 40°C.