Pipothiazine
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Pipothiazine is a phenothiazine tranquillizer. Pipothiazine is used in psychotic disorder, agitation and confusion.
Indications
Pipothiazine is primarily indicated in conditions like Post-operative nausea and vomiting, Psychosis.
Contraindications
Pipothiazine is contraindicated in conditions like Bone marrow depression, Coma, Narrow-angle glaucoma, CNS depression.
Side Effects
The severe or irreversible adverse effects of Pipothiazine, which give rise to further complications include Hemolytic anemia, Tardive dyskinesia, Leucopenia, Agranulocytosis, Hypothermia, Leukocytosis, Cardiovascular symptoms. Pipothiazine produces potentially life-threatening effects which include Neuroleptic Malignant Syndrome. which are responsible for the discontinuation of Pipothiazine therapy. The signs and symptoms that are produced after the acute overdosage of Pipothiazine include Extrapyramidal effects. The symptomatic adverse reactions produced by Pipothiazine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Constipation, Insomnia, Dry mouth, Impotence, Depression, Nasal congestion, Nightmares, Galactorrhea, Pallor.
Warnings
Pipothiazine should be used with caution in patients exposed to extreme heat or phosphorus insecticides, patients in state of alcohol withdrawal, patients with history of peptic ulcer, allergic reactions, with renal impairment, prostatic hypertrophy. Photosensitization may occur, caution patients to take appropriate measures (e.g. wear protective clothing or sunscreen) against exposure to sunlight or UV light. Discontinue use at least 48 hrs before myelography.
High Risk Groups
Drug should not be given to Pediatrics, Pregnant Mothers, Geriatrics, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
0.142 to 2.857 mg/kg (1.5 (1.4995)) 24 hourly PO — -
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
Pipothiazine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholVORICONAZOLEVoriconazole may increase the serum concentration of pipotiazine by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Inj Protect from Sunlight.
Available Brands in Pakistan
No brands are recorded for this generic.