Pirenzepine (di HCl)
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Pirenzepine (di HCl) is a selective M1 antimuscarinic agent, which has a preferential action on the gastric mucosa, causing reduced gastric acid secretion. Pirenzepine (di HCl) is used in the management of peptic ulcer disease.
Indications
Pirenzepine (di HCl) is primarily indicated in conditions like Benign gastric ulcer, Duodenal ulcer.
Contraindications
Pirenzepine (di HCl) is contraindicated in conditions like Renal failure.
Side Effects
The signs and symptoms that are produced after the acute overdosage of Pirenzepine (di HCl) include Anticholinergic effects. The symptomatic adverse reactions produced by Pirenzepine (di HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dry mouth, Disturbances of accommodation.
Warnings
Pirenzepine should be used with caution in patients with renal (kidney) impairment, particularly those with end-stage renal failure. Avoid use in patients with angle closure glaucoma.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
0.238 to 0.714 mg/kg (0.48 (0.476)) 8 hourly PO — -
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
No data regarding the interactions of Pirenzepine (di HCl) was found.
Storage
Tab Protect from Moisture.
Available Brands in Pakistan
No brands are recorded for this generic.