Porcine Insulin
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Porcine Insulin is a type of soluble Insulin extracted from the pancreas of porcus a pig or hog, contains 51 amino acid arranged in two chains (A and B) joined together by disulfide linkage. It differs from human insulin in only one amino acid in the beta chain. Porcine Insulin is a short-acting form of insulin, used in the management of diabetes mellitus, and diabetic ketoacidosis.
Indications
Porcine Insulin is primarily indicated in conditions like Diabetes mellitus, Hyperkalemia.
Contraindications
Porcine Insulin is contraindicated in conditions like Hypersensitivity to the drug.
Side Effects
Porcine Insulin produces potentially life-threatening effects which include Hypoglycemia, which are responsible for the discontinuation of Porcine Insulin therapy. The symptomatic adverse reactions produced by Porcine Insulin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Lipohypertrophy.
Warnings
Patients should be instructed regarding their dosage and should be reminded that this formulation requires the administration of a smaller volume of solution than is the case with less concentrated formulations.
High Risk Groups
Drug should not be given to Pregnant Mothers, and Cardiac / Hypertensive Patients.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
0.05 to 0.2 IU/kg (0.12 (0.125)) 12 hourly IV — Dose depends upon Blood Sugar Level
5 to 10 IU/kg (7.5 (7.5)) 12 hourly SC — Dose depends upon Blood Sugar Level
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Porcine Insulin is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAdrenalineAlcoholAspirinCaptoprilACE inhibitors (e.g Captopril) possibly enhance hypoglycemic effect of insulin. Chlorpromazine (HCl)Clonidine (HCl)CyclophosphamideDiltiazem (HCl)GuanethidineIsoniazidMetformin (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Inj Store at room temperature or refrigerator. Do not Freeze. Protect from Sunlight. Use within 2 yrs (at 4C) if refrigerated and within 1 month if kept at room temperature.
Available Brands in Pakistan
No brands are recorded for this generic.