Probucol
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
It is used to lower cholesterol. It is used to lower triglycerides.
Indications
It is used to lower cholesterol. It is used to lower triglycerides.
Contraindications
Probucol is contraindicated in conditions like Cardiac arrhythmia, Diarrhea.
Side Effects
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your
doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
Signs of an allergic reaction, like rash ; hives; itching ; red, swollen, blistered, or peeling skin with or without fever ; wheezing ;
tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue,
or throat. Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or
yellow skin or eyes. A fast heartbeat . A heartbeat that does not feel normal. Chest pain or pressure. Very bad dizziness or passing out. Ringing in ears. A burning, numbness, or tingling feeling that is not normal. Sweating a lot. Any unexplained bruising or bleeding. Very bad muscle pain or weakness. Not able to pass urine or change in how much urine is passed.
Warnings
Determine serum lipid level before treatment. If satisfactory lipid alteration is not achieved discontinue therapy.
High Risk Groups
Drug should not be given to Pediatrics, Pregnant Mothers, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
7.14 mg/kg (7.1 (7.14)) 12 hourly PO — -
Child Dosage
Safety not established ( ) —
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Probucol is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementArtemisininColestipol (HCl)Colestipol (HCl)LycopeneCholesterol-lowering drugs and fat substitutes,may decrease the absorption of lycopene may decrease the absorption of lycopeneVORICONAZOLEAdditive QTc prolongation may occur. Consider alternate therapy or monitor for QTc prolongation These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tab Store in a well closed container, at room temperature. Protect from Sunlight and Moisture.
Available Brands in Pakistan
No brands are recorded for this generic.