Proguanil (HCl)
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Proguanil (HCl) is antimalarial agent. Proguanil (HCl) is a dihydrofolate reductase inhibitor. Proguanil (HCl) is a biguanide derivative.
Indications
Proguanil (HCl) is primarily indicated in conditions like Duodenal ulcer associated with H.Pylori, Malaria, Malaria prophylaxis.
Contraindications
Proguanil (HCl) is contraindicated in conditions like Renal failure,Renal diseases.
Side Effects
The signs and symptoms that are produced after the acute overdosage of Proguanil (HCl) include Vomiting, Diarrhea, Hematuria, Abdominal pain. The symptomatic adverse reactions produced by Proguanil (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Alopecia, Skin reactions, Stomatitis, Epigastric discomfort, Mouth ulcers, Asthenia, Anorexia, Dyspepsia, Gastritis, Fever, Cough.
Warnings
Proguanil should be used with caution in people with impaired kidney function. Pregnant women should take folic acid supplements.
High Risk Groups
Drug should not be given to patients suffering from Kidney dysfunction. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
1.5 mg/kg (1.5 (1.5)) 12 hourly PO — -
Child Dosage
5 mg/kg (5 (5)) 24 hourly Oral — -
Neonatal Dosage
3.125 mg/kg (3.1 (3.125)) 24 hourly Oral —
Drug Interactions
No data regarding the interactions of Proguanil (HCl) was found.
Storage
Tab Store Below 30°C. Protect from Sunlight and Moisture.
Available Brands in Pakistan
No active brands are currently recorded for this generic.
1 record is present but flagged "Unverified / Legacy" and excluded.