Pharmapedia Pro
Medicines/Generics/Propranolol (HCl)

Propranolol (HCl)

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

Spot an error in this entry? Submit a correction
Overview
Propranolol is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure may reduce the risk of stroke and heart attacks. Propranolol is also used to treat severe chest pain (angina), migraine headaches, or hypertrophic subaortic stenosis (thickened heart muscle). This medicine may also be used to treat irregular heartbeats, tremors, or pheochromocytoma (adrenal gland tumor). It may also be used to reduce the risk of death in patients who have heart attacks. Propranolol oral solution is used to treat proliferating infantile hemangioma. This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart. This medicine is available only with your doctor's prescription.
Indications
Propranolol is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure may reduce the risk of stroke and heart attacks. Propranolol is also used to treat severe chest pain (angina), migraine headaches, or hypertrophic subaortic stenosis (thickened heart muscle). This medicine may also be used to treat irregular heartbeats, tremors, or pheochromocytoma (adrenal gland tumor). It may also be used to reduce the risk of death in patients who have heart attacks. Propranolol oral solution is used to treat proliferating infantile hemangioma. This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart. This medicine is available only with your doctor's prescription.
Contraindications
Propranolol (HCl) is contraindicated in conditions like Acidosis, Asthma, COPD, Heart failure, Cardiogenic shock, Bronchospasm, Hemorrhage, Heart block.
Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Chest tightness cough producing mucus difficulty with breathing Incidence not known Black, tarry stools blistering, peeling, or loosening of the skin blood in the urine bloody nose bloody stools blurred or loss of vision body aches or pain burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings chest pain or discomfort confusion about identity, place, and time congestion constipation cough cracks in the skin crying decreased awareness or responsiveness decreased urine output depersonalization diarrhea difficulty with swallowing dilated neck veins disturbed color perception dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position double vision dryness or soreness of the throat dysphoria euphoria fast, pounding, slow, or irregular heartbeat fever and chills general feeling of discomfort, illness, or weakness hair loss halos around lights headaches heavier menstrual periods hoarseness irregular breathing lightheadedness, dizziness, or fainting loss of heat from the body mental depression mimicry of speech or movements muscle or joint pain mutism nausea negativism night blindness noisy breathing overbright appearance of lights paleness or cold feeling in the fingertips and toes paranoia peculiar postures or movements, mannerisms, or grimacing pinpoint red or purple spots on the skin puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue quick to react or overreact emotionally rapidly changing moods rectal bleeding red skin lesions, often with a purple center red, irritated eyes red, swollen skin reddening of the skin, especially around the ears runny nose scaly skin seeing, hearing, or feeling things that are not there severe sleepiness short-term memory loss skin irritation or rash, including rash that looks like psoriasis skin rash, hives, or itching stomach pain and tenderness sores, ulcers, or white spots in the mouth or on the lips sweating swelling of the eyes, face, fingers, feet, or lower legs swollen glands tender, swollen glands in the neck tingling or pain in fingers or toes when exposed to cold tunnel vision unusual bleeding or bruising unusual tiredness or weakness voice changes vomiting weight gain Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Anxiety dry mouth hyperventilation irritability restlessness shaking sleepiness or unusual drowsiness trouble sleeping unusual dreams Less common Decreased appetite Incidence not known Dry eyes heartburn loss of strength or energy muscle weakness pain or discomfort in the chest, upper stomach, or throat stomach cramps unusual drowsiness, dullness, or feeling of sluggishness vivid dreams Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Warnings
Propranolol should be used with caution in diabetic patients and patients with kidney or liver disease.
High Risk Groups
Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, Geriatrics, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
10 to 40 mg (25 (25)) 8 hourly PO —
Child Dosage
0.25 to 0.5 mg/kg (0.38 (0.375)) 8 hourly Oral — -
Neonatal Dosage
0.25 to 0.5 mg/kg (0.38 (0.375)) 8 hourly Oral — -
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Rizatriptan Thioridazine Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Abametapir Albuterol Bupivacaine Bupivacaine Liposome Bupropion Capmatinib Ceritinib Clonidine Crizotinib Darunavir Desvenlafaxine Diatrizoate Diltiazem Dronedarone Epinephrine Escitalopram Eslicarbazepine Acetate Fedratinib Fenoldopam Fexinidazole Fingolimod Fluoxetine Formoterol Haloperidol Indacaterol Iobenguane I 131 Iohexol Lacosamide Lercanidipine Levalbuterol Lidocaine Mefloquine Mepivacaine Olodaterol Oxymetazoline Pixantrone Ponesimod Prilocaine Rivastigmine Salmeterol Simeprevir Siponimod Sparsentan Terbutaline Venlafaxine Verapamil Vilanterol Zileuton Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Acarbose Aceclofenac Acemetacin Acetyldigoxin Albiglutide Alfuzosin Alogliptin Aluminum Carbonate, Basic Aluminum Hydroxide Aluminum Phosphate Amtolmetin Guacil Aspirin Bromfenac Bufexamac Bunazosin Calcium Carbonate Canagliflozin Celecoxib Chlorpromazine Chlorpropamide Cholestyramine Choline Salicylate Cimetidine Clonixin Dapagliflozin Deslanoside Dexibuprofen Dexketoprofen Diclofenac Diflunisal Digitoxin Digoxin Dihydroergotamine Dihydroxyaluminum Aminoacetate Dihydroxyaluminum Sodium Carbonate Dipyrone Doxazosin Droxicam Dulaglutide Empagliflozin Ergotamine Ertugliflozin Etodolac Etofenamate Etoricoxib Exenatide Felbinac Fenoprofen Fepradinol Feprazone Flecainide Floctafenine Flufenamic Acid Flurbiprofen Fluvoxamine Glimepiride Glipizide Glyburide Ibuprofen Indomethacin Insulin Aspart, Recombinant Insulin Degludec Insulin Detemir Insulin Glargine, Recombinant Insulin Glulisine Insulin Human Inhaled Insulin Human Isophane (NPH) Insulin Human Regular Insulin Lispro, Recombinant Ketoprofen Ketorolac Linagliptin Liraglutide Lixisenatide Lornoxicam Loxoprofen Lumiracoxib Magaldrate Meclofenamate Mefenamic Acid Meloxicam Metformin Metildigoxin Miglitol Morniflumate Moxisylyte Nabumetone Naproxen Nateglinide Nepafenac Niflumic Acid Nimesulide Nimesulide Beta Cyclodextrin Oxaprozin Oxyphenbutazone Parecoxib Phenoxybenzamine Phentolamine Phenylbutazone Piketoprofen Pioglitazone Piroxicam Pramlintide Pranoprofen Prazosin Proglumetacin Propyphenazone Proquazone Quinidine Repaglinide Rifapentine Rofecoxib Rosiglitazone Salicylic Acid Salsalate Saxagliptin Sitagliptin Sodium Salicylate St John's Wort Sulindac Tamsulosin Tenoxicam Terazosin Tiaprofenic Acid Tolazamide Tolbutamide Tolfenamic Acid Tolmetin Trimazosin Urapidil Valdecoxib Vildagliptin
Storage
Inj, Oral Soln Store at room temperature. Do not Freeze. Protect from Sunlight. Tab Store in a well closed container, Below 40°C. Protect from Sunlight and Moisture.