Prothionamide
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Prothionamide used in the treatment of tuberculous (T.B.). The actions, uses similar to ethionamide.
Indications
Prothionamide is primarily indicated in conditions like Leprosy, Tuberculosis.
Contraindications
Prothionamide is contraindicated in conditions like Hepatic disease, General dose, Chronic resistant vaginal candidiasis.
Side Effects
The severe or irreversible adverse effects of Prothionamide, which give rise to further complications include Liver damage, Hepatitis, GI dysfunction. Prothionamide produces potentially life-threatening effects which include Convulsions, Hepatitis. which are responsible for the discontinuation of Prothionamide therapy. The symptomatic adverse reactions produced by Prothionamide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Sleepiness, Headache, Insomnia, Depression, Paresthesias.
Warnings
Prothionamide should not be given to patients with severe liver disease. It is suggested that Prothionamide should be avoided during pregnancy or in women of child bearing potentials unless the benefits outweigh its possible hazards.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
1.79 to 7.14 mg/kg (4.5 (4.465)) 12 hourly PO — -
Child Dosage
Dose not established for children ( ) —
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Prothionamide was found.
Storage
Tab, Inj
Available Brands in Pakistan
No brands are recorded for this generic.