Quinapril
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Quinapril is used in adults alone or in combination with other medications to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack .
Quinapril is also used in adults together with other medications to treat heart failure .
Quinapril may also be used for purposes not listed in this medication guide.
Indications
Quinapril is used in adults alone or in combination with other medications to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack .
Quinapril is also used in adults together with other medications to treat heart failure .
Quinapril may also be used for purposes not listed in this medication guide.
Contraindications
You should not use quinapril if you are allergic to it, or if:
have a history of angioedema; or you are allergic to any other ACE inhibitor, such as benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril , ramipril, or trandolapril .
Do not take quinapril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).
If you have diabetes, do not use quinapril together with any medication that contains aliskiren (a blood pressure medicine).
You may also need to avoid taking quinapril with aliskiren if you have kidney disease.
Tell your doctor if you have ever had:
a connective tissue disease such as Marfan syndrome , Sjogren's syndrome , lupus, scleroderma , or rheumatoid arthritis ; heart problems; low blood pressure ; high blood levels of potassium ( hyperkalemia ); if you are on a low-salt diet; low white blood cell counts; diabetes; kidney disease (or if you are on dialysis); or liver disease .
Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Quinapril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.
Ask a doctor if it is safe to breastfeed while using this medicine.
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Quinapril may cause serious side effects. Call your doctor at once if you have:
chest pain, fast, slow, or uneven heart rate; a light-headed feeling, like you might pass out; heart problems --swelling, rapid weight gain, feeling short of breath; kidney problems --swelling, urinating less, feeling tired or short of breath; liver problems --loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes), abnormal liver function tests; signs of infection --fever, chills, sore throat , body aches, unusual tiredness, loss of appetite, bruising or bleeding; or high blood potassium --nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.
Common side effects of quinapril may include:
headache; nausea, vomiting, stomach pain; cough; or dizziness, tiredness.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Do not use if you are pregnant. Stop using quinapril and tell your doctor right away if you become pregnant.
You should not use quinapril if you have ever had angioedema. Do not take quinapril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).
If you have diabetes, do not use quinapril together with any medication that contains aliskiren (a blood pressure medicine).
High Risk Groups
Do not use if you are pregnant. Stop using quinapril and tell your doctor right away if you become pregnant.
You should not use quinapril if you have ever had angioedema. Do not take quinapril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).
If you have diabetes, do not use quinapril together with any medication that contains aliskiren (a blood pressure medicine).
Adult Dosage
20 to 40 mg (30 (30)) 24 hourly PO — Maintenance.
5 to 10 mg (7.5 (7.5)) 24 hourly PO — Initial dose.
Scraped Dose — Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Your blood pressure will need to be checked often. Your kidney or liver function may also need to be tested.
Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking quinapril. This can lead to very low blood pressure, electrolyte disorders, or kidney failure .
Tell your doctor if you have a planned surgery.
If you have high blood pressure, keep using quinapril even if you feel well. High blood pressure often has no symptoms.
Store tightly closed at room temperature, away from moisture and heat.
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
Tell your doctor about all your other medicines, especially:
lithium; a diuretic or "water pill"; gold injections to treat arthritis; temsirolimus , sirolimus, or everolimus ; or NSAIDs (nonsteroidal anti-inflammatory drugs) --aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin , meloxicam, and others.
This list is not complete. Other drugs may affect quinapril, including prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible drug interactions are listed here.
Storage
Tab Store Below 40°C. Protect from Sunlight and Moisture.