Ramipril

Ramipril is used to treat high blood pressure (hypertension) or congestive heart failure to reduce the risk of cardiovascular events, strokes, and myocardial infarctions. Ramipril is an ACE inhibitor . ACE stands for angiotensin-converting enzyme. Ramipril may also be used for purposes not listed in this medication guide.

Ramipril is used to treat high blood pressure (hypertension) or congestive heart failure to reduce the risk of cardiovascular events, strokes, and myocardial infarctions. Ramipril is an ACE inhibitor . ACE stands for angiotensin-converting enzyme. Ramipril may also be used for purposes not listed in this medication guide.

You should not use ramipril if you are allergic to it, or if: you have a history of angioedema; you recently took a heart medicine called sacubatril; or if you are allergic to any other ACE inhibitor, such as benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, or trandolapril. Do not take ramipril within 36 hours before or after taking medicine that contains sacubatril (such as Entresto). If you have diabetes, do not use ramipril together with any medication that contains aliskiren (such as Tekturna or Tekamlo). You may also need to avoid taking ramipril with aliskiren if you have kidney disease. To make sure this medicine is safe for you, tell your doctor if you have ever had: kidney disease (or if you are on dialysis); liver disease; a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis; or if you are also taking telmisartan (Micardis). Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Ramipril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control. It is not known whether ramipril passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

Get emergency medical help if you have any signs of an allergic reaction to ramipril: hives; severe stomach pain; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: a light-headed feeling, like you might pass out; jaundice (yellowing of your skin or eyes); little or no urination; fever, chills, sore throat, cold or flu symptoms; or high potassium - nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement. Common ramipril side effects may include: headache; cough; or dizziness, weakness, tired feeling. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Do not use ramipril if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. You should not use ramipril if you have ever had angioedema. Do not take this medicine within 36 hours before or after taking medicine that contains sacubatril (such as Entresto). If you have diabetes, do not use ramipril together with any medication that contains aliskiren (such as Tekturna or Tekamlo).

Do not use ramipril if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. You should not use ramipril if you have ever had angioedema. Do not take this medicine within 36 hours before or after taking medicine that contains sacubatril (such as Entresto). If you have diabetes, do not use ramipril together with any medication that contains aliskiren (such as Tekturna or Tekamlo).

2.5 mg (2.5 (2.5)) 24 hourly PO — Initially in 1-2 div.doses. 2.5 to 5 mg (3.8 (3.75)) 24 hourly PO — Maintenance Scraped Dose — Take ramipril exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended. Ramipril can be taken with or without food. Swallow the tablet whole. You may open the capsule and sprinkle the medicine into a half-cup (4 ounces) of water, apple juice, or applesauce to make swallowing easier. Swallow without chewing. You may store the mixture for up to 24 hours at room temperature, or up to 48 hours in a refrigerator. If using the oral solution, use an oral dosing syringe or oral dosing cup to correctly measure the prescribed amount of medication. You can obtain these from your pharmacy. Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking ramipril. This can lead to very low blood pressure, electrolyte disorders, or kidney failure. Your blood pressure will need to be checked often, and you may need frequent blood tests to check your potassium levels. Drink plenty of water each day while you are taking this medication. If you need surgery, tell the surgeon ahead of time that you are using this medicine. If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. Store at the tablets and capsules at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use. Store the oral suspension in a refrigerator at 2°C to 8°C (36°F to 46°F). Keep it in its original packaging. After the bottle is opened, store it between 20°C to 25°C (68°F to 77°F) and use within 60 days.

( ) — Not recommended in this age group

( ) — Not recommended in this age group

Ramipril is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholAlprostadilEnhanced hypotensive effects when alprostadil given with ACE inhibitors (e.g Ramipril)IndomethacinLithiumTelmisartanWhen co-administering telmisartan and ramipril, the response may be greater because of the possibly additive pharmacodynamic effects of the combined drugs, and also because of the increased exposure to ramipril and ramiprilat in the presence of telmisartan.Moderate These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Caps Store Below 40°C. Protect from Sunlight and Moisture.