Ranolazine
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Ranolazine is used in adults to treat chronic angina (chest pain). Ranolazine is not for use during an acute (emergency) attack of angina.
Ranolazine may also be used for purposes not listed in this medication guide.
Indications
Ranolazine is used in adults to treat chronic angina (chest pain). Ranolazine is not for use during an acute (emergency) attack of angina.
Ranolazine may also be used for purposes not listed in this medication guide.
Contraindications
You should not take ranolazine if you are allergic to it, or if you have:
cirrhosis of the liver.
Some drugs should not be used with ranolazine. Your treatment plan may change if you also use:
clarithromycin ; nefazodone ; St. John's wort ; antifungal medicine -- itraconazole , ketoconazole ; HIV or AIDS medicine --indinavir, lopinavir/ritonavir , nelfinavir , ritonavir, saquinavir; seizure medicine -- carbamazepine , phenobarbital , phenytoin; or tuberculosis medicine --rifabutin, rifampin, rifapentine .
Tell your doctor if you have ever had:
long QT syndrome (in you or a family member); liver disease ; or kidney disease.
Tell your doctor if you are pregnant or breastfeeding.
Side Effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Ranolazine may cause serious side effects. Call your doctor at once if you have:
a light-headed feeling; fast or pounding heartbeats, fluttering in your chest, shortness of breath , and sudden dizziness (like you might pass out); or kidney problems --swelling, urinating less, feeling tired or short of breath.
Common side effects of ranolazine may include:
nausea, constipation ; headache; or dizziness.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
You should not take ranolazine if you have cirrhosis of the liver.
Tell your doctor about all your other medicines. Some drugs should not be used with ranolazine.
High Risk Groups
You should not take ranolazine if you have cirrhosis of the liver.
Tell your doctor about all your other medicines. Some drugs should not be used with ranolazine.
Adult Dosage
500 to 1000 mg (750 (750)) 12 hourly oral — May be taken with or without food. Dose adjustments may be needed when taken with other drugs.
Scraped Dose — Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
You may take ranolazine tablets with or without food.
Open the pack of ranolazine granules and mix the medicine with a tablespoon of soft food such as applesauce or yogurt. Swallow the mixture right away without crushing or chewing.
Ranolazine granules can also be given through a feeding tube. Ask your doctor or pharmacist if you do not understand these instructions.
Swallow the tablet whole and do not crush, chew, or break it.
Chronic angina is often treated with a combination of drugs. Do not change your dose or dosing schedule without your doctor's advice.
Call your doctor if your symptoms do not improve, or if they get worse.
You may need medical tests to check your heart and kidney function.
Store at room temperature away from moisture and heat.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Tell your doctor about all your current medicines. Many drugs can affect ranolazine, especially:
any other medicine to treat heart disease ; an antibiotic or antifungal medicine; oral diabetes medicine; medicine to prevent organ transplant rejection; medicine to treat a mental illness; or medicine to treat or prevent nausea and vomiting caused by chemotherapy or radiation.
This list is not complete and many other drugs may affect ranolazine. This includes prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible drug interactions are listed here.
Storage
tablet Store Between 15°C-30°C.
Available Brands in Pakistan
2 active brands listed alphabetically.
RANOLA
ActiveHIGHNOON LABORATORIES LTD.
DML: RANOLA
Tabs
RANZOL
ActiveMAPLE PHARMACEUTICALS (PVT) LTD
DML: RANZOL
Tabs SR
1 additional record is present but flagged "Unverified / Legacy" and not listed.
