Remifentanil
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Remifentanil is an opioid analgesic similar to fentanyl, used as an adjunct to general anaesthesia. Remifentanil is given as an induction agent since it has a rapid onset of action and an extremely short duration of action. Remifentanil is metabolized very rapidly by blood and non-specific tissue esterases, making its pharmacokinetic and pharmacodynamic half-lives extremely short.
Indications
Remifentanil is primarily indicated in conditions like Anesthesia induction, Anesthesia maintenance, Conscious analgesia, Analgesia immediate post-op period.
Contraindications
Remifentanil is contraindicated in conditions like Phaeochromocytoma, Raised intracranial pressure, Adjunct in cryptococcal meningitis.
Side Effects
The symptomatic adverse reactions produced by Remifentanil are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Nausea, Vomiting, Constipation, Respiratory depression, Bradycardia, Hypotension/hypertension, Shivering, Apnea, Hypoxia, Biliary tract disease.
Warnings
Skilled activities such as driving should be avoided because of drowsiness.
High Risk Groups
If prescribing authority justifies the benefits of the drug against the possible damages, he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
No adult dosage information is recorded for this medicine yet.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Remifentanil was found.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No brands are recorded for this generic.