Repaglinide
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Repaglinide is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus . repaglinide is not for treating type 1 diabetes.
Repaglinide may also be used for purposes not listed in this medication guide.
Indications
Repaglinide is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus . repaglinide is not for treating type 1 diabetes.
Repaglinide may also be used for purposes not listed in this medication guide.
Contraindications
You should not use repaglinide if you are allergic to it, or if you have:
severe liver disease; or diabetic ketoacidosis (call your doctor for treatment).
Many drugs can interact with repaglinide and some drugs should not be used at the same time. Your doctor may change your treatment plan if you also use:
clopidogrel ; cyclosporine ; gemfibrozil; or NPH insulin (such as isophane insulin).
Tell your doctor if you have ever had:
liver disease; or if you also take metformin or other diabetes medicines.
Follow your doctor's instructions about using repaglinide if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.
You should not breastfeed while using repaglinide.
Repaglinide is not approved for use by anyone younger than 18 years old.
Side Effects
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat , burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Repaglinide may cause serious side effects. Call your doctor at once if you have:
pale or yellowed skin, dark colored urine, fever, confusion or weakness; or pancreatitis --severe pain in your upper stomach spreading to your back, nausea and vomiting.
Common side effects of repaglinide may include:
low blood sugar ; nausea, diarrhea; headache, back pain ; joint pain ; or cold symptoms such as stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
You should not use repaglinide if you have type 1 diabetes , severe liver disease , or diabetic ketoacidosis .
You should not use repaglinide together with gemfibrozil or NPH insulin (such as isophane insulin).
High Risk Groups
You should not use repaglinide if you have type 1 diabetes , severe liver disease , or diabetic ketoacidosis .
You should not use repaglinide together with gemfibrozil or NPH insulin (such as isophane insulin).
Adult Dosage
0.5 to 2 mg (1.2 (1.25)) 8 hourly PO — Maximum dose: 4 mg.
Scraped Dose — Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Repaglinide is usually taken 2 to 4 times daily, within 30 minutes before eating a meal. Follow your doctor's instructions. If you skip a meal, do not take your dose of repaglinide. Wait until your next meal.
Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office.
You may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia , eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).
Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.
Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.
Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.
Repaglinide is only part of a treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely.
Store repaglinide at room temperature away from moisture and heat.
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
Many other medicines that can increase or decrease the effects of repaglinide on lowering your blood sugar. Some drugs can also cause you to have fewer symptoms of hypoglycemia, making it harder to tell when your blood sugar is low. This includes prescription and over-the-counter medicines, vitamins, and herbal products . Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
4 active brands listed alphabetically.
NOVIREP
ActiveNOVINS INTERNATIONAL
DML: NOVIREP
Tabs
NOVONORM
ActiveNOVO NORDISK SCIENTIFIC OFFICE
DML: NOVONORM
Tabs
RAPTROL
ActiveWILSHIRE LABORATORIES (PVT) LTD.
DML: RAPTROL
Tabs
REPAGLIN
ActiveRAAZEE THERAPUTICS (PVT) LTD.
DML: REPAGLIN
Tabs
5 additional records are present but flagged "Unverified / Legacy" and not listed.
