Rifaximin
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Rifaximin is used to treat travelers' diarrhea caused by Escherichia coli (E. coli) in adults and children who are at least 12 years old. Most people get this infection by eating food or drinking fluids that have been contaminated with the E. coli bacteria.
Rifaximin is also used to treat irritable bowel syndrome (IBS) in adults whose main symptom is diarrhea.
Rifaximin is also used to lower the risk of a decline in brain function in adults with liver failure. Brain function can be affected when the liver stops working and cannot remove toxic substances from the body.
Rifaximin may also be used for purposes not listed in this medication guide.
Indications
Rifaximin is used to treat travelers' diarrhea caused by Escherichia coli (E. coli) in adults and children who are at least 12 years old. Most people get this infection by eating food or drinking fluids that have been contaminated with the E. coli bacteria.
Rifaximin is also used to treat irritable bowel syndrome (IBS) in adults whose main symptom is diarrhea.
Rifaximin is also used to lower the risk of a decline in brain function in adults with liver failure. Brain function can be affected when the liver stops working and cannot remove toxic substances from the body.
Rifaximin may also be used for purposes not listed in this medication guide.
Contraindications
You should not take rifaximin if you are allergic to rifaximin, rifabutin , rifampin, or rifapentine .
Tell your doctor if you have ever had:
liver disease ; diarrhea with a fever; or watery or bloody diarrhea.
Tell your doctor if you are pregnant or breastfeeding.
Rifaximin should not be given to a child younger than 12 years old.
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Rifaximin may cause serious side effects. Call your doctor at once if you have:
severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose); fever; or fluid build-up around the stomach --rapid weight gain, stomach pain and bloating, trouble breathing while lying down.
Common side effects of rifaximin may include:
swelling in your hands or feet; nausea; headache, dizziness; tiredness; or abnormal liver function tests.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
High Risk Groups
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Adult Dosage
200 mg (200 (200)) 8 hourly oral — It can be taken with or without food.
550 mg (550 (550)) 12 hourly oral — This is indicated for reduction in risk of overt hepatic encephalopathy recurrence in patients 18 years of age.
Scraped Dose — Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
You may take rifaximin with or without food.
For travelers' diarrhea, rifaximin is usually taken for only 3 days. For IBS, rifaximin is usually taken for 2 weeks at a time. Follow your doctor's dosing instructions very carefully.
Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Rifaximin will not treat a viral infection such as the flu or a common cold .
Do not share this medicine with another person , even if they have the same symptoms you have.
Call your doctor if your symptoms do not improve after 24 to 48 hours, or if they get worse while using rifaximin.
Rifaximin does not treat all bacterial forms of travelers' diarrhea.
Store at room temperature away from moisture and heat.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Tell your doctor about all your other medicines, especially:
cyclosporine ; ketoconazole ; warfarin (Coumadin, Jantoven); an antibiotic -- clarithromycin , erythromycin ; antiviral medicine --ritonavir, saquinavir ; or heart or blood pressure medicine -- amiodarone , quinidine , verapamil .
This list is not complete. Other drugs may affect rifaximin, including prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible drug interactions are listed here.
Storage
Store Between 15°C-25°C.
Available Brands in Pakistan
3 active brands listed alphabetically.
NIMIXA
ActiveGETZ PHARMA PAKISTAN (PVT) LTD.
DML: NIMIXA
Tabs
RIFAXA
ActiveFEROZSONS LABORATOIES LTD.
DML: RIFAXA
Tabs
XIFAXA
ActiveBROOKES PHARMACEUTICAL LABORATORIES (PAK.) LTD.
DML: XIFAXA
Tabs
2 additional records are present but flagged "Unverified / Legacy" and not listed.
