Medicines/Generics/Ropinirole (HCl)

Ropinirole (HCl)

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

Spot an error in this entry? Submit a correction

Overview

Ropinirole (HCl) is a dopamine receptor agonist, used for the treatment of Parkinson`s disease. Ropinirole (HCl) is also used with levodopa in more advanced disease. It may also be used for the treatment of moderate-to-severe primary Restless Legs Syndrome (RLS) in adults.

Indications

Ropinirole (HCl) is primarily indicated in conditions like Idiopathic Parkinson's disease (PD) and Restless legs syndrome (RLS).

Contraindications

Ropinirole (HCl) is contraindicated in conditions like Hypersensitivity, Pregnancy, Lactation.

Side Effects

The severe or irreversible adverse effects of Ropinirole (HCl), which give rise to further complications include Hallucinations, Cardiac arrhythmias, Confusion, Anxiety, Psychosis, Depression, Postural hypotension, Amnesia. The signs and symptoms that are produced after the acute overdosage of Ropinirole (HCl) include Nausea, Vomiting, Confusion, Dizziness, Agitation, Orthostatic hypotension, Chest pain, Dystonia. The symptomatic adverse reactions produced by Ropinirole (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Abdominal pain, Confusion, Leg edema.

Warnings

Ropinirole should be used with caution in patients with mild to moderate hepatic impairment and renal impairment (avoid in severe); severe cardiovascular disease; major psychotic disorders; avoid abrupt withdrawal.

High Risk Groups

Drug should not be given to Pediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Adult Dosage

0.25 mg (0.25 (0.25)) 8 hourly PO — Initial dose for 1st week. 0.5 mg (0.5 (0.5)) 8 hourly PO — Dose for 2nd week. 0.75 mg (0.75 (0.75)) 8 hourly PO — Dose for 3rd week. 1 mg (1 (1)) 8 hourly PO — Dose for 4th week. After week 4, if necessary, daily dosage may be increased by 1.5 mg/day on a weekly basis up to a dose of 9 mg/day, and then by up to 3 mg/day weekly to a total dose of 24 mg/day

Child Dosage

No child dosage information is recorded for this medicine yet.

Neonatal Dosage

No neonatal dosage information is recorded for this medicine yet.

Drug Interactions

No data regarding the interactions of Ropinirole (HCl) was found.

Storage

Tab Store Below 25°C. Protect from Sunlight and Moisture.