Sargramostim
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Sargramostim is a man-made form of a protein that stimulates the growth of white blood cells in your body. White blood cells help your body fight against infection .
Sargramostim is used in adults and children who are at least 2 years old, to help prevent serious infection in conditions such as leukemia , bone marrow transplant, and pre-chemotherapy blood cell collection.
Sargramostim is also used to lower the risk of death from bone marrow suppression after exposure to radiation in adults and children as young as newborns.
Sargramostim may also be used for purposes not listed in this medication guide.
Indications
Sargramostim is a man-made form of a protein that stimulates the growth of white blood cells in your body. White blood cells help your body fight against infection .
Sargramostim is used in adults and children who are at least 2 years old, to help prevent serious infection in conditions such as leukemia , bone marrow transplant, and pre-chemotherapy blood cell collection.
Sargramostim is also used to lower the risk of death from bone marrow suppression after exposure to radiation in adults and children as young as newborns.
Sargramostim may also be used for purposes not listed in this medication guide.
Contraindications
You should not use sargramostim if you are allergic to sargramostim, filgrastim , or yeast.
Sargramostim may contain an ingredient that can cause serious side effects or death in very young or low birth-weight babies. Do not give this medicine to a child without medical advice.
Tell your doctor if you have ever had:
heart disease ; lung disease; an allergy to benzyl alcohol ; or a buildup of fluid around your lungs (also called pleural effusion ).
Using sargramostim may increase your risk of tumor growth or blood cancers. Ask your doctor about these risks.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
You should not breast-feed while using sargramostim and for at least 2 weeks after your last dose.
Side Effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your caregiver if you feel dizzy, nauseated, sweaty, light-headed, short of breath, or have chest tightness or fast heartbeats.
Capillary leak syndrome is a rare but serious side effect of sargramostim. Call your doctor right away if you have signs of this condition: stuffy or runny nose followed by tiredness, thirst, decreased urination, trouble breathing, and sudden swelling or weight gain.
Sargramostim may cause serious side effects. Call your doctor at once if you have:
pain when you breathe, feeling short of breath while lying down; chest pain or pressure; fast or slow heartbeats; pain or burning when you urinate; easy bruising, unusual bleeding, purple or red spots under your skin; increased blood pressure --severe headache , blurred vision, pounding in your neck or ears, anxiety , nosebleed; or liver problems --loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Your sargramostim doses may be delayed or permanently discontinued if you have certain side effects.
Common side effects of sargramostim may include:
swelling, breathing problems; stomach pain, nausea, vomiting , diarrhea ; loss of appetite, weight loss ; urination problems; fever, weakness, not feeling well; mouth sores; headache, high blood pressure ; numbness, tingling, rash, itching; hair loss ; or abnormal blood tests.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Do not use sargramostim within 24 hours before you receive chemotherapy or radiation, or within 24 hours after chemotherapy.
High Risk Groups
Do not use sargramostim within 24 hours before you receive chemotherapy or radiation, or within 24 hours after chemotherapy.
Adult Dosage
250 mcg/m² (250 (250)) As recommended. IV Infusion —
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
If you also receive chemotherapy or radiation: Do not use sargramostim within 24 hours before you receive chemotherapy or radiation, or within 24 hours after chemotherapy.
Other drugs may affect sargramostim, including prescription and over-the-counter medicines, vitamins , and herbal products . Tell your doctor about all your current medicines and any medicine you start or stop using.
Storage
Store in a well closed container, Below -15°C. Do not Freeze.
Available Brands in Pakistan
No brands are recorded for this generic.