Semustine
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Semustine is a nitrosourea. It is one of group of antineoplastic drugs known as alkylating agent.
Indications
Semustine is primarily indicated in conditions like Brain tumors, Colorectal cancer, Lymphomas, Stomach cancer.
Contraindications
Semustine is contraindicated in conditions like Hypersensitivity.
Side Effects
The severe or irreversible adverse effects of Semustine, which give rise to further complications include Renal damage, Thrombocytopenia.The signs and symptoms that are produced after the acute overdosage of Semustine include Convulsions, Pulmonary fibrosis, Leucopenia, Optic neuritis.The symptomatic adverse reactions produced by Semustine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea and vomiting, Hyperpigmentation.
Warnings
Used with caution in children who are at risk of severe delayed pul;monary toxicity, reduced lung function. Blood counts should be monitored weekly. Renal and hepatic functions should be monitored periodically.
High Risk Groups
Drug should not be given to patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
No adult dosage information is recorded for this medicine yet.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Semustine was found.
Storage
Inj Store in a well closed container, . Protect from Sunlight and Heat.
Available Brands in Pakistan
No brands are recorded for this generic.