Sertraline (HCl)

Sertraline (Zoloft) is a medication used for depression , panic disorders , obsessive-compulsive disorder (OCD), social anxiety disorder (SAD), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD). Sertraline is thought to work by balancing serotonin, a naturally occurring chemical messenger that affects mood and emotions. Sertraline is an SSRI (serotonin reuptake inhibitor ) that increases serotonin levels between neurons (nerves) by blocking serotonin from being absorbed. Serotonin is sometimes called 5-hydroxytryptamine (5-HT). The original sertraline brand name is Zoloft , which was FDA-approved on December 30, 1991, and it is now also available as a generic medicine. It is available as sertraline 50mg tablets, 25mg tablets, 100mg tablets, 150mg capsules, 200mg capsules, and an oral solution of 20 mg/mL.

Sertraline (Zoloft) is a medication used for depression , panic disorders , obsessive-compulsive disorder (OCD), social anxiety disorder (SAD), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD). Sertraline is thought to work by balancing serotonin, a naturally occurring chemical messenger that affects mood and emotions. Sertraline is an SSRI (serotonin reuptake inhibitor ) that increases serotonin levels between neurons (nerves) by blocking serotonin from being absorbed. Serotonin is sometimes called 5-hydroxytryptamine (5-HT). The original sertraline brand name is Zoloft , which was FDA-approved on December 30, 1991, and it is now also available as a generic medicine. It is available as sertraline 50mg tablets, 25mg tablets, 100mg tablets, 150mg capsules, 200mg capsules, and an oral solution of 20 mg/mL.

You should not use sertraline if you are allergic to it, or if you also take pimozide . Do not use the liquid form of this medicine if you take disulfiram ( Antabuse ). if you have used an MAO inhibitor in the past 14 days, a dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine. Wait at least 14 days after stopping an MAO inhibitor before you take sertraline. Tell your doctor if you also take stimulant medicine, opioid medicine, herbal products , or medicine for depression , mental illness, Parkinson's disease , migraine headaches, serious infections, or prevention of nausea and vomiting . An interaction with sertraline could cause a serious condition called serotonin syndrome. To make sure sertraline is safe for you, tell your doctor if you have ever had: an allergy or sensitivity to aspirin or tartrazine (food dye) or latex (Zoloft oral solution - the dropper dispenser contains natural rubber); bipolar disorder (manic depression); heart disease, high blood pressure , or a stroke; liver or kidney disease; seizures ; glaucoma ; bleeding problems, or if you take warfarin ( Coumadin , Jantoven ); long QT syndrome ; or low levels of sodium in your blood. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Your doctor will need to check your progress on a regular basis. Your family or caregivers should also watch for sudden changes in your behavior. Sertraline is approved for use in children at least 6 years old, only to treat obsessive-compulsive disorder but not depression.

The symptomatic adverse reactions produced by Sertraline (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Fatigue, Nausea, Diarrhea, Palpitation, Insomnia, Somnolence, Xerostomia, Ejaculatory Failure, Dry mouth, Tremor, Dyspepsia, Agitation, Decreased appetite, Hyperhidrosis, Libido decreased, Constipation, Erectile dysfunction.

People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Tell your doctor right away if you have any sudden changes in mood or behavior, or thoughts about suicide. Do not stop taking sertraline without your doctor's advice. Seek medical attention right away if you have symptoms of serotonin syndrome , such as agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. This medicine can increase the risk of bleeding. Taking aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk. This medicine may cause activation of mania or hypomania, so screen patients with bipolar disorder. Sertraline should be used with caution in patients with seizure disorders. Angle-closure glaucoma: Avoid the use of sertraline in patients with untreated anatomically narrow angles. This medicine may cause symptoms of sexual dysfunction. You should not use sertraline if you also take pimozide or if you are being treated with methylene blue injection.

People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Tell your doctor right away if you have any sudden changes in mood or behavior, or thoughts about suicide. Do not stop taking sertraline without your doctor's advice. Seek medical attention right away if you have symptoms of serotonin syndrome , such as agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. This medicine can increase the risk of bleeding. Taking aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk. This medicine may cause activation of mania or hypomania, so screen patients with bipolar disorder. Sertraline should be used with caution in patients with seizure disorders. Angle-closure glaucoma: Avoid the use of sertraline in patients with untreated anatomically narrow angles. This medicine may cause symptoms of sexual dysfunction. You should not use sertraline if you also take pimozide or if you are being treated with methylene blue injection.

50 mg (50 (50)) 24 hourly PO — Initially for 2 Weeks 50 to 200 mg (120 (125)) 24 hourly PO — Maintenance for 1 Month Scraped Dose — Take sertraline exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Take sertraline with or without food, in the morning or evening, but at the same time each day. Capsules : Swallow the capsule whole, and do not crush, chew, break, or open it. Oral liquid (oral concentrate): This must be diluted with only water, ginger ale, lemon/lime soda, lemonade, or orange juice right before you take it. Read and carefully follow all mixing instructions provided with your medicine. Ask your doctor or pharmacist if you need help. Measure the mixed medicine with the supplied syringe or the dose-measuring device (not a kitchen spoon). Sertraline may cause false results on a drug-screening urine test. Tell the laboratory staff that you use this medicine. Do not stop using sertraline suddenly, or you could have unpleasant symptoms (such as agitation , confusion, tingling, or electric shock feelings). Ask your doctor before stopping the medicine.

Safety not established ( ) —

No neonatal dosage information is recorded for this medicine yet.

Sertraline can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma , heart problems, high blood pressure, depression, mental illness, cancer, malaria , or HIV . Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin , ibuprofen , naproxen , Advil , Aleve , Motrin , and others. Using an NSAID with sertraline may cause you to bruise or bleed easily. Other drugs may interact with sertraline, including prescription and over-the-counter medicines, vitamins , and herbal products . Tell your doctor about all other medicines you use.Where can I get more information? Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use sertraline only for the indication prescribed.

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