Sitosterol
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Sitosterol an antihyperlipidemic agent. Due to the structural similarity to cholesterol, Sitosterol competitively inhibits the absorption of cholesterol. Sitosterol used to lower high blood cholesterol levels. Sitosterol lower the risk of heart attack by preventing the formation of plaque into the blood vessels.
Indications
Sitosterol is primarily indicated in conditions like Benign prostatic hyperplasia, Hyperlipidemia.
Contraindications
Sitosterol is contraindicated in conditions like Pregnancy, Sitosterolemia, Breast feeding.
Side Effects
The symptomatic adverse reactions produced by Sitosterol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Diarrhea, Constipation, Indigestion, Erectile dysfunction, Loss of libido, Gas.
Warnings
It should not be used in patients with rare genetic disorder, Sitosterolemia, Cerebroendodontic, Xanthomatosis. It's supplementation should be avoided in pregnant and nursing mothers.
High Risk Groups
Drug should not be given to Pregnant Mothers. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
0.29 mg/kg (0.29 (0.29)) 8 hourly PO — -
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
Plant sterols reduce the absorption of the fat-soluble vitamins beta-carotene, alpha-carotene, and vitamin E. No effects on vitamins A and K have been noted. Beta-sitosterol levels may decrease in patients receiving ezetimibe through its inhibition of intestinal absorption of plant sterols.
Storage
Caps Store in a well closed container, . Protect from Sunlight, Moisture and Heat.
Available Brands in Pakistan
No brands are recorded for this generic.