Sodium Calciumedetate
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Sodium Calcium edetate is a chelating agent. Sodium Calcium edetate is used in the treatment of lead poisonings.
Indications
Sodium Calcium edetate is primarily indicated in conditions like Lead poisoning, Skin diseases.
Contraindications
Sodium Calcium edetate is contraindicated in conditions like Renal insufficiency.
Side Effects
The severe or irreversible adverse effects of Sodium Calcium edetate, which give rise to further complications include Renal tubular changes. The symptomatic adverse reactions produced by Sodium Calcium edetate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Thirst, Headache, Fatigue, Malaise, Nausea and vomiting, Urinary urgency, Urinary frequency.
Warnings
Sodium calcium edetate should be used with caution in patients with impaired renal function. Regular monitoring of renal function for proteinuria and hematuria has been recommended. It should not be given by mouth in the treatment of lead poisoning.
High Risk Groups
Drug should not be given to patients suffering from Kidney dysfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
14.29 mg/kg.hr (14 (14.29)) 12 hourly IV Inf — Upto 2.1-2.8 Hours for 5 Days
Child Dosage
40 mg/kg (40 (40)) 12 hourly IV Infusion — Treat for up to 5 days
Neonatal Dosage
40 mg/kg (40 (40)) 12 hourly IV Infusion — Treat up to 5 days
Drug Interactions
Sodium Calciumedetate is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAmphotericin BInsulinConcurrent use will decrease the duration of action of zinc insulin preparations by chelation of zinc.Zinc ChlorideConcurrent use may decrease the effectiveness of edetate calcium disodium and zinc supplements due to chelation.Zinc supplement therapy should be withheld until edetate calcium disodium therapy is completed.Zinc CitrateConcurrent use may decrease the effectiveness of edetate calcium disodium and zinc supplements due to chelation.Zinc supplement therapy should be withheld until edetate calcium disodium therapy is completed.Zinc OxideConcurrent use may decrease the effectiveness of edetate calcium disodium and zinc supplements due to chelation.Zinc supplement therapy should be withheld until edetate calcium disodium therapy is completed.Zinc PhenolsulphonateConcurrent use may decrease the effectiveness of edetate calcium disodium and zinc supplements due to chelation.Zinc supplement therapy should be withheld until edetate calcium disodium therapy is completed.Zinc PyrithioneConcurrent use may decrease the effectiveness of edetate calcium disodium and zinc supplements due to chelation.Zinc supplement therapy should be withheld until edetate calcium disodium therapy is completed.Zinc SulphateConcurrent use may decrease the effectiveness of edetate calcium disodium and zinc supplements due to chelation.Zinc supplement therapy should be withheld until edetate calcium disodium therapy is completed. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Inj Store Below 40°C.
Available Brands in Pakistan
No brands are recorded for this generic.