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Medicines/Generics/Sodium Diatrizoate

Sodium Diatrizoate

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview
It is used before an x-ray or an alike test.
Indications
It is used before an x-ray or an alike test.
Contraindications
Sodium Diatrizoate is contraindicated in conditions like Hypersensitivity.
Side Effects
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All products: Signs of an allergic reaction, like rash; hives; itching ; red, swollen, blistered, or peeling skin with or without fever; wheezing ; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Shortness of breath . Fast or abnormal heartbeat. Very bad dizziness or passing out. A very bad skin reaction ( Stevens-Johnson syndrome / toxic epidermal necrolysis ) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes. Injection: Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain. Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight. Seizures. Very bad headache . Feeling agitated. Feeling confused. Chest pain or pressure. Blue or gray skin color. Pain where the shot was given. This medicine may cause tissue damage if the drug leaks from the vein. Tell your nurse if you have any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your body.
Warnings
It should be used with caution in patients with previous reaction to diatrizoates or any other iodinated contrast agent and patient with allergies to other drugs. Diatrizoate should be administered with great caution in patients with asthma and history of allergy, and should be avoided to patients with known hypersensitivity to iodine or contrast media. An IV injection of 0.5 to 1 ml of contrast media has been given as a test for sensitivity before administration of main dose. Caution is needed in patients with severe hepatic (liver) or renal impairment or who may be at a risk of renal failure. Dehydration patients should have their fluid and electrolyte balance corrected before administration of contrast medium. It should be used with extreme caution in patients with hypertension, cardiac disease, pheochromocytoma, sickle-cell anemia or hypothyroidism. Avoid use during pregnancy.
High Risk Groups
Drug should not be given to Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
500 to 1000 mL (750 (750)) As recommended. PO — Enema, from 500 mL to 1000 mL of a 15 to 25 percent solution. 90 to 180 mL (140 (135)) As recommended. PO — 90-180 mL of a 25 to 40 percent solution.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Sodium Diatrizoate is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementFamotidineShould not be use concurrently without informing doctor.LansoprazoleShould not be use concurrently without informing doctor.OmeprazoleShould not be use concurrently without informing doctor.RanitidineShould not be use concurrently without informing doctor.Sodium IpodateRisk of renal toxicity may be increased when administration of Sodium Ipodate is followed by Sodium Diatrizoate, especially in patients with hepatic or biliary function impairment.Technetium Tc-99m OxidronatePossible renal and hepatic uptake if diatrizoate sodium is administered intravenously immediately after technetium Tc 99m oxidronate. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Soln Store Below 25°C. Protect from Sunlight.

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