Sodium Salicylate
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Sodium Salicylate reduces fever and relieves pain. It is used in the symptomatic therapy of gout and in acute rheumatic fever.
Indications
Sodium Salicylate is primarily indicated in conditions like Fever, Pain, Rheumatoid arthritis.
Contraindications
Sodium Salicylate is contraindicated in conditions like Peptic ulcer, Renal diseases, Gastritis.
Side Effects
The severe or irreversible adverse effects of Sodium Salicylate, which give rise to further complications include Hepatotoxicity, Gastric irritation, Mucosal lesions, Worsening of pre-existing heart failure. Sodium Salicylate produces potentially life-threatening effects which include Hypersensitivity reactions, Reye's syndrome. which are responsible for the discontinuation of Sodium Salicylate therapy. The signs and symptoms that are produced after the acute overdosage of Sodium Salicylate include Acidosis, Fever, Hyperglycemia, Hypoglycemia, Renal failure, Respiratory alkalosis. The symptomatic adverse reactions produced by Sodium Salicylate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Tachycardia, Rashes, Hyperventilation, Metabolic acidosis, Respiratory alkalosis, Salicylism.
Warnings
Sodium salicylate should be used with caution in patients with chronic renal (kidney) insufficiency, gastric ulcer, severe anemia, patients intolerant to salicylate.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
1.74 to 14.29 mg/kg (8 (8.015)) 24 hourly Slow IV — -
4.64 to 8.57 mg/kg (6.6 (6.605)) 4 hourly PO — -
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
Sodium Salicylate is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholFludrocortisone (Acetate)MethotrexateSalicylates interfere with the excretion of methotrexate and may displace it from binding site result in increased toxicity.MajorMonitor patient for signs and symptoms of bone marrow suppression and nephrotoxicity.ProbenecidSpironolactoneTeniposideConcurrent use may result in potentiation of drug toxicity.Warfarin (Na) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No brands are recorded for this generic.