Sodium Stibogluconate
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Sodium Stibogluconate is antiprotozoal, used in the treatment of all types of leishmaniasis along with other drugs (eg; pentamidine and amphotericin B).
Indications
Sodium Stibogluconate is primarily indicated in conditions like Leishmaniasis, Visceral leishmaniasis.
Contraindications
Sodium Stibogluconate is contraindicated in conditions like Renal diseases, Pneumonia, Liver diseases, Heart disease, Complicating secondary infection, Previous antimonial therapy.
Side Effects
The severe or irreversible adverse effects of Sodium Stibogluconate, which give rise to further complications include Venous thrombosis. Sodium Stibogluconate produces potentially life-threatening effects which include Hepatotoxicity, Cardiotoxicity, Renal toxicity. which are responsible for the discontinuation of Sodium Stibogluconate therapy. The signs and symptoms that are produced after the acute overdosage of Sodium Stibogluconate include Renal failure, Circulatory collapse, Disseminated intravascular coagulopathy. The symptomatic adverse reactions produced by Sodium Stibogluconate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Anorexia, Myalgia, Malaise, Arthralgia, Nausea and vomiting.
Warnings
Safety of the sodium stibogluconate has not been determined in pregnant women , in the children
High Risk Groups
Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, Geriatrics, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
8.57 mg/kg (8.6 (8.57)) 24 hourly IM — For 7-10 Days
8.57 mg/kg (8.6 (8.57)) 24 hourly Slow IV — For 7-10 Days
Child Dosage
10 mg/kg (10 (10)) 24 hourly Intra Muscular — -
10 mg/kg (10 (10)) 24 hourly Intra Venous — -
Neonatal Dosage
10 mg/kg (10 (10)) 24 hourly Intra Muscular — -
10 mg/kg (10 (10)) 24 hourly Intra Venous — -
Drug Interactions
No data regarding the interactions of Sodium Stibogluconate was found.
Storage
IV Inj, IM Inj Store Below 25°C. Protect from Sunlight.
Available Brands in Pakistan
No active brands are currently recorded for this generic.
1 record is present but flagged "Unverified / Legacy" and excluded.