Sodium Thiosulphate
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Sodium Thiosulphate used in the treatment of cyanide or arsenic poisoning in conjunction with sodium nitrite.
Indications
Sodium Thiosulphate is primarily indicated in conditions like Cyanide poisoning, Poisoning with cyanogenic substances, Skin diseases.
Contraindications
Sodium Thiosulphate is contraindicated in conditions like Hypersensitivity to any component of product.
Side Effects
The severe or irreversible adverse effects of Sodium Thiosulphate, which give rise to further complications include Irritation, Itching, Hives. Sodium Thiosulphate produces potentially life-threatening effects which include Hypotension. which are responsible for the discontinuation of Sodium Thiosulphate therapy. The symptomatic adverse reactions produced by Sodium Thiosulphate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Burning, Stinging on application.
Warnings
Discontinue topical use if irritation or sensitivity occurs. Can increase risk of thiocyanate intoxication. Safety in pregnancy has not been established. Discontinue topical use if irritation or sensitivity occurs
High Risk Groups
Drug should not be given to Pregnant Mothers, and Cardiac / Hypertensive Patients. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
17.86 mg/kg.min (18 (17.86)) 24 hourly IV Inf — For 10 Minutes
Child Dosage
250 mg/kg (250 (250)) As recommended. Slow IV — Given over 10 Minutes
Neonatal Dosage
250 mg/kg (250 (250)) As recommended. Slow IV — Given over 10 Minutes
Drug Interactions
No data regarding the interactions of Sodium Thiosulphate was found.
Storage
Inj, lotions Store in a well closed container, . Protect from Moisture and Heat.
Available Brands in Pakistan
No brands are recorded for this generic.